# Transforming growth factor, beta 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28558652](https://www.wikidata.org/wiki/Q28558652)  
**Source**: https://4ort.xyz/entity/transforming-growth-factor-beta-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17246)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
6. [Cloning and expression of glucocorticoid-induced genes in fetal rat lung fibroblasts. Transforming growth factor-beta 3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
7. [Transforming growth factor-beta induces cellular injury in experimental diabetic neuropathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
8. [Betaglycan can act as a dual modulator of TGF-beta access to signaling receptors: mapping of ligand binding and GAG attachment sites](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
9. [Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
10. [Transforming growth factor ß1 and ß2 (TGFβ2 / TGFβ2) profile changes in previously irradiated free flap beds](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
11. [Activation of rat alveolar macrophage-derived latent transforming growth factor beta-1 by plasmin requires interaction with thrombospondin-1 and its cell surface receptor, CD36](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
12. [Localization of transforming growth factors, TGFbeta1 and TGFbeta3, in hypothalamic magnocellular neurones and the neurohypophysis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
13. [Immunohistochemical localization of connective tissue growth factor, transforming growth factor‐beta1 and phosphorylated‐smad2/3 in the developing periodontium of rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
14. [Proteoglycan expression in bleomycin lung fibroblasts: role of transforming growth factor-beta(1) and interferon-gamma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
15. [Hypoxia induces transforming growth factor-beta1 gene expression in the pulmonary artery of rats via hypoxia-inducible factor-1alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
16. [Differential effects of transforming growth factor-beta1 on cellular proliferation in the developing prostate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
17. [Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
18. [TGF-β1, released by myofibroblasts, differentially regulates transcription and function of sodium and potassium channels in adult rat ventricular myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
19. [Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
20. [TGF-beta expression during rat pregnancy and activity on decidual cell survival](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
21. [Transforming growth factor-beta(s) and their receptors in aging rat prostate](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
22. [Urocortin ameliorates diabetic nephropathy in obese db/db mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
23. [Acetaldehyde stimulates the activation of latent transforming growth factor-beta1 and induces expression of the type II receptor of the cytokine in rat cultured hepatic stellate cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
24. [Astrocyte-derived transforming growth factor-{beta} mediates the neuroprotective effects of 17{beta}-estradiol: involvement of nonclassical genomic signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
25. [Changes in TGF-β receptors of rat hepatocytes during primary culture and liver regeneration: Increased expression of TGF-β receptors associated with increased sensitivity to TGF-β-mediated growth inhibition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
26. [Customized platelet-rich plasma with transforming growth factor β1 neutralization antibody to reduce fibrosis in skeletal muscle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
27. [The impact of 1,25-dihydroxyvitamin D3 on the expression of connective tissue growth factor and transforming growth factor-β1 in the myocardium of rats with diabetes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
28. [Cellular and molecular events associated with the bone-protecting activity of the noncalcemic vitamin D analog Ro-26-9228 in osteopenic rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
29. [Microarray analysis of mechanical shear effects on flexor tendon cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
30. [Upregulation of interleukin‐1β/transforming growth factor‐β1 and hypoxia relate to molecular mechanisms underlying immobilization‐induced muscle contracture](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
31. [The effect of antibodies to TGF-beta1 and TGF-beta2 at a site of sciatic nerve repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
32. [Tissue concentration of transforming growth factor beta1 and basic fibroblast growth factor in skin wounds created with a CO2 laser and scalpel: a comparative experimental study, using an animal model of skin resurfacing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
33. [A preliminary study on the changes of expression of PDGF-beta, PDGFR-beta, TGF-beta 1, TGFR, bFGF and its relationship with the wound age in wound healing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
34. [Role for TGF-beta1, FGF-2 and PDGF-AA in a myelination of CNS aggregate cultures enriched with macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
35. [Effects of TGF-betas and a specific antagonist on apoptosis of immature rat male germ cells in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
36. [X-linked inhibitor of apoptosis (XIAP) inhibits c-Jun N-terminal kinase 1 (JNK1) activation by transforming growth factor beta1 (TGF-beta1) through ubiquitin-mediated proteosomal degradation of the TGF-beta1-activated kinase 1 (TAK1)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
37. [Ontogenic expression of TGFbeta 1, 2, and 3 and its receptors in the rat gastric mucosa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
38. [Expression of TGFbeta family in the developing internal ear of rat embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
39. [A dual role for TGF-beta1 in the control and persistence of fungal pneumonia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
40. [Antigen presentation by vaginal cells: role of TGFbeta as a mediator of estradiol inhibition of antigen presentation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
41. [TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
42. [Alternative neural crest cell fates are instructively promoted by TGFbeta superfamily members](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
43. [Involvement of transforming growth factor-beta in regulation of calcium transients in diabetic vascular smooth muscle cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
44. [Tgf-beta1, Tgf-beta2, Tgf-beta3 and Msx2 expression is elevated during frontonasal suture morphogenesis and during active postnatal facial growth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
45. [Mechanical stretch via transforming growth factor-β1 activates microRNA-208a to regulate hypertrophy in cultured rat cardiac myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
46. [Effect of radiation and repeated sub-culturing on the transforming growth factor-β1 signaling pathway in FRTL-5 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
47. [Effects of dexamethasone exposure on rat metanephric development: in vitro and in vivo studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
48. [Role of the spleen in liver regeneration in relation to transforming growth factor-β1 and hepatocyte growth factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
49. [Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)
50. [Alcohol Alters Insulin‐Like Growth Factor‐1‐Induced Transforming Growth Factor β1 Synthesis in the Medial Basal Hypothalamus of the Prepubertal Female Rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17246)