# transforming growth factor alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q3740187](https://www.wikidata.org/wiki/Q3740187)  
**Source**: https://4ort.xyz/entity/transforming-growth-factor-alpha-q3740187


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P01135)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01135&geneProductId=UniProtKB:P01135)
6. [EGF receptor-independent action of TGF-alpha protects Naked2 from AO7-mediated ubiquitylation and proteasomal degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
7. [Myristoylated Naked2 escorts transforming growth factor alpha to the basolateral plasma membrane of polarized epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
8. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
9. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
10. [Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
11. [Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
12. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01135&geneProductId=UniProtKB:P01135)
13. [Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
15. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
16. [Unique carboxyl-terminal sequences of wild type and alternatively spliced variant forms of transforming growth factor-alpha precursors mediate specific interactions with ErbB4 and ErbB2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
17. [TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
18. [Naked2 acts as a cargo recognition and targeting protein to ensure proper delivery and fusion of TGF-alpha containing exocytic vesicles at the lower lateral membrane of polarized MDCK cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
19. [TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01135&geneProductId=UniProtKB:P01135)
20. [Transforming growth factor-alpha-mediated growth pathways in human gastro-intestinal cell lines in relation to the gastrin autocrine pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01135)
21. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P01135&geneProductId=UniProtKB:P01135)
22. Ensembl Release 99
23. UMLS 2023