# Transcription factor AP-2 alpha

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21106376](https://www.wikidata.org/wiki/Q21106376)  
**Source**: https://4ort.xyz/entity/transcription-factor-ap-2-alpha-q21106376


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P05549)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
5. [Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
6. [Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
7. [Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
8. [Cloning and characterization of a second AP-2 transcription factor: AP-2 beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
9. [A family of AP-2 proteins down-regulate manganese superoxide dismutase expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
10. [Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
11. [Expression of Human Frataxin Is Regulated by Transcription Factors SRF and TFAP2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
12. [A family of AP-2 proteins down-regulate manganese superoxide dismutase expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
13. [Epigenetic regulation of HYAL-1 hyaluronidase expression. identification of HYAL-1 promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
14. [Derepression of the C/EBPα gene during adipogenesis: Identification of AP-2α as a repressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
15. [Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
16. [Dual association by TFAP2A during activation of the p21cip/CDKN1A promoter](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
17. [Derepression of the C/EBPα gene during adipogenesis: Identification of AP-2α as a repressor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
18. [AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
19. [AP-2alpha Inhibits c-MYC Induced Oxidative Stress and Apoptosis in HaCaT Human Keratinocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
20. [Tau promoter confers neuronal specificity and binds Sp1 and AP-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
21. [The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
22. [Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
23. [Myosin VI isoform localized to clathrin-coated vesicles with a role in clathrin-mediated endocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
24. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
25. [Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
26. [Nucleophosmin acts as a novel AP2alpha-binding transcriptional corepressor during cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
27. [Sumoylation pathway is required to maintain the basal breast cancer subtype](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
28. [Cloning and characterization of a second AP-2 transcription factor: AP-2 beta](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
29. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
30. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
31. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
32. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
33. [Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
34. [The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
35. [AP2 transcription factor induces apoptosis in retinoblastoma cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
36. [AP2 transcription factor induces apoptosis in retinoblastoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
37. [Genotype-phenotype analysis of the branchio-oculo-facial syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
38. [BCOR regulates mesenchymal stem cell function by epigenetic mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
39. [An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P05549&geneProductId=UniProtKB:P05549)
40. [An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P05549)
41. Ensembl Release 99