# transcription factor 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21111604](https://www.wikidata.org/wiki/Q21111604)  
**Source**: https://4ort.xyz/entity/transcription-factor-3-q21111604


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15923)
3. Q20641742
4. [Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
6. [Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
7. [Increased expression of the FIGLA transcription factor is associated with primordial follicle formation in the human fetal ovary](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
8. [E2A basic-helix-loop-helix transcription factors are negatively regulated by serum growth factors and by the Id3 protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
9. [Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
10. [Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
11. [A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
12. [Regulation of E2A activities by histone acetyltransferases in B lymphocyte development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
13. [Promotion of cell cycle progression by basic helix-loop-helix E2A](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
14. [Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
15. [Human Hand1 basic helix-loop-helix (bHLH) protein: extra-embryonic expression pattern, interaction partners and identification of its transcriptional repressor domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
16. [Differential regulation of Hand1 homodimer and Hand1-E12 heterodimer activity by the cofactor FHL2](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
17. [Mixed lineage kinase phosphorylates transcription factor E47 and inhibits TrkB expression to link neuronal death and survival pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
18. [Selective use of multiple vitamin D response elements underlies the 1 alpha,25-dihydroxyvitamin D3-mediated negative regulation of the human CYP27B1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
19. [Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
20. [HEB and E2A function as SMAD/FOXH1 cofactors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
21. [Neurogenin3 activates the islet differentiation program while repressing its own expression](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
22. [Neurogenin3 activates the islet differentiation program while repressing its own expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
23. [Regulation of scleraxis function by interaction with the bHLH protein E47](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
24. [Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
25. [Saethre-Chotzen mutations cause TWIST protein degradation or impaired nuclear location](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
26. [HEB and E2A function as SMAD/FOXH1 cofactors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
27. [Regulation of scleraxis function by interaction with the bHLH protein E47](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
28. [Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
29. [Notch signaling induces rapid degradation of achaete-scute homolog 1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
30. [Mutations affecting the BHLHA9 DNA-binding domain cause MSSD, mesoaxial synostotic syndactyly with phalangeal reduction, Malik-Percin type](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
31. [Association of erythroid transcription factors: complexes involving the LIM protein RBTN2 and the zinc-finger protein GATA1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
32. [Differential genomic targeting of the transcription factor TAL1 in alternate haematopoietic lineages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
33. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
34. [SCL binds the human homologue of DRG in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
35. [LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
36. [HASH-1 and E2-2 are expressed in human neuroblastoma cells and form a functional complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
37. [LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
38. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
39. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
40. [A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
41. [Mutations in NEUROD1 are associated with the development of type 2 diabetes mellitus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
42. [LMO4 controls the balance between excitatory and inhibitory spinal V2 interneurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
43. [Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
44. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
45. [Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
46. [Basic helix-loop-helix transcription factor epicardin/capsulin/Pod-1 suppresses differentiation by negative regulation of transcription](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
47. [Long-term cultured E2A-deficient hematopoietic progenitor cells are pluripotent](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
48. [Regulation of E2A activities by histone acetyltransferases in B lymphocyte development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P15923)
49. [E2A and IRF-4/Pip promote chromatin modification and transcription of the immunoglobulin kappa locus in pre-B cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)
50. [The basic helix-loop-helix transcription factor scleraxis regulates fibroblast collagen synthesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15923&geneProductId=UniProtKB:P15923)