# Trans-acting transcription factor 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14888116](https://www.wikidata.org/wiki/Q14888116)  
**Source**: https://4ort.xyz/entity/trans-acting-transcription-factor-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O89090)
3. Q20641742
4. [Mammalian SP/KLF transcription factors: bring in the family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
6. [Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
7. [Sp1 site is crucial for the mouse claudin-19 gene expression in the kidney cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
8. [Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
9. [Activation of mouse RAG-2 promoter by Myc-associated zinc finger protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
10. [Differential utilization of the promoter of peripheral-type benzodiazepine receptor by steroidogenic versus nonsteroidogenic cell lines and the role of Sp1 and Sp3 in the regulation of basal activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
11. [STAT5 proteins are involved in down-regulation of iron regulatory protein 1 gene expression by nitric oxide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
12. [Transcriptional regulation of murine beta1,4-galactosyltransferase in somatic cells. Analysis of a gene that serves both a housekeeping and a mammary gland-specific function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
13. [Regulation of aldehyde reductase expression by STAF and CHOP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
14. [Combinatorial cis-acting elements control tissue-specific activation of the cardiac troponin I gene in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
15. [Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
16. [Transcription Factor NF-Y Is a Functional Regulator of the Transcription of Core Clock Gene Bmal1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
17. [High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
18. [Interaction of HSF1 and HSF2 with the Hspa1b promoter in mouse epididymal spermatozoa](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
19. [Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
20. [Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
21. [mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
23. [Kr-pok increases FASN expression by modulating the DNA binding of SREBP-1c and Sp1 at the proximal promoter](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
24. [Transcription Factor NF-Y Is a Functional Regulator of the Transcription of Core Clock Gene Bmal1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
25. [Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
26. [Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
27. [Mice lacking MHC class II molecules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
28. [Induction of dystrophin Dp71 expression during neuronal differentiation: opposite roles of Sp1 and AP2alpha in Dp71 promoter activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
29. [Induction of dystrophin Dp71 expression during neuronal differentiation: opposite roles of Sp1 and AP2alpha in Dp71 promoter activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
30. [NF-I/Sp1 switch elements regulate collagen alpha 1(I) gene expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
31. [Isolation of a gene encoding a functional zinc finger protein homologous to erythroid Krüppel-like factor: identification of a new multigene family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
32. [A role for nucleoprotein Zap3 in the reduction of telomerase activity during embryonic stem cell differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
33. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
34. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
35. [Specificity protein 1-zinc finger protein 179 pathway is involved in the attenuation of oxidative stress following brain injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
36. [Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
37. [RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
38. [Transcription of the catalytic 180-kDa subunit gene of mouse DNA polymerase alpha is controlled by E2F, an Ets-related transcription factor, and Sp1](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
39. [Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
40. [A Far Upstream, Cell Type-specific Enhancer of the Mouse Thrombospondin 3 Gene Is Located within Intron 6 of the Adjacent Metaxin Gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
41. [Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
42. [Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?protein=O89090&geneProductId=UniProtKB:O89090)
43. [Superoxide dismutase-3 promotes full expression of the EPO response to hypoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
44. [RNA polymerase II subunit 3 is retained in the cytoplasm by its interaction with HCR, the psoriasis vulgaris candidate gene product](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
45. [A Far Upstream, Cell Type-specific Enhancer of the Mouse Thrombospondin 3 Gene Is Located within Intron 6 of the Adjacent Metaxin Gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
46. [Augmented IL-10 production and redox-dependent signaling pathways in glucose-6-phosphate dehydrogenase-deficient mouse peritoneal macrophages](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
47. [Sp1/Sp3 compound heterozygous mice are not viable: impaired erythropoiesis and severe placental defects](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
48. [The TBN Protein, which Is Essential for Early Embryonic Mouse Development, Is an Inducible TAFII Implicated In Adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
49. [The mechanism of biogenesis and potential function of the two alternatively spliced mRNAs encoded by the murine Msx3 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O89090)
50. ensembl Release 106