# TPX2 microtubule nucleation factor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21115409](https://www.wikidata.org/wiki/Q21115409)  
**Source**: https://4ort.xyz/entity/tpx2-microtubule-nucleation-factor-q21115409


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9ULW0)
3. Q20641742
4. [Identification of Genes (SPON2 and C20orf2) Differentially Expressed between Cancerous and Noncancerous Lung Cells by mRNA Differential Display](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
6. [GM130 Regulates Golgi-Derived Spindle Assembly by Activating TPX2 and Capturing Microtubules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
7. [The nuclear scaffold protein SAF-A is required for kinetochore–microtubule attachment and contributes to the targeting of Aurora-A to mitotic spindles](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
8. [Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
9. [Phosphorylation of SAF-A/hnRNP-U Serine 59 by Polo-Like Kinase 1 Is Required for Mitosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
10. [Systematic identification of SH3 domain‐mediated human protein–protein interactions by peptide array target screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
11. [Structural Basis of Aurora-A Activation by TPX2 at the Mitotic Spindle](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
12. [Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
13. [Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
14. [A single amino acid change converts Aurora-A into Aurora-B-like kinase in terms of partner specificity and cellular function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
15. [Modulation of kinase‐inhibitor interactions by auxiliary protein binding: Crystallography studies on Aurora A interactions with VX‐680 and with TPX2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
16. [A Cancer-associated Aurora A Mutant Is Mislocalized and Misregulated Due to Loss of Interaction with TPX2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
17. [p100: a novel proliferation-associated nuclear protein specifically restricted to cell cycle phases S, G2, and M](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
18. [TOGp, the Human Homolog of XMAP215/Dis1, Is Required for Centrosome Integrity, Spindle Pole Organization, and Bipolar Spindle Assembly](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
19. [Building a spindle of the correct length in human cells requires the interaction between TPX2 and Aurora A](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ULW0)
20. Ensembl Release 99