# Tout-velu Dmel_CG10117

> protein found in Drosophila melanogaster

**Wikidata**: [Q29814757](https://www.wikidata.org/wiki/Q29814757)  
**Source**: https://4ort.xyz/entity/tout-velu-dmel-cg10117


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9V730)
3. Q20641742
4. [Distinct and collaborative roles of Drosophila EXT family proteins in morphogen signalling and gradient formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
5. [Heparan sulfate polymerization in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
6. [Glycosylation of proteins in plants and invertebrates.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
7. [Heparan sulfate polymerization in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
9. [Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
10. [Tout-velu is a Drosophila homologue of the putative tumour suppressor EXT-1 and is needed for Hh diffusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
12. [Structural analysis of glycosaminoglycans in animals bearing mutations in sugarless, sulfateless, and tout-velu. Drosophila homologues of vertebrate genes encoding glycosaminoglycan biosynthetic enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
13. [Structural analysis of glycosaminoglycans in Drosophila and Caenorhabditis elegans and demonstration that tout-velu, a Drosophila gene related to EXT tumor suppressors, affects heparan sulfate in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
14. [Abrogation of heparan sulfate synthesis in Drosophila disrupts the Wingless, Hedgehog and Decapentaplegic signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
15. [Reception of Slit requires only the chondroitin-sulphate-modified extracellular domain of Syndecan at the target cell surface](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
16. [Hedgehog does not guide migrating Drosophila germ cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
17. [toutvelu, a regulator of heparan sulfate proteoglycan biosynthesis, controls guidance cues for germ-cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
18. [Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
19. [Cell surface heparan sulfate proteoglycans: selective regulators of ligand-receptor encounters](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
20. [Cholesterol modification of proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
21. [Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
22. [Hedgehog movement is regulated through tout velu-dependent synthesis of a heparan sulfate proteoglycan](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
23. [Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
24. [Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
25. [Specificities of heparan sulphate proteoglycans in developmental processes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9V730&geneProductId=UniProtKB:Q9V730)
26. [Three Drosophila EXT genes shape morphogen gradients through synthesis of heparan sulfate proteoglycans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
27. [Demonstration of a novel gene DEXT3 of Drosophila melanogaster as the essential N-acetylglucosamine transferase in the heparan sulfate biosynthesis: chain initiation and elongation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
28. [Cell type-specific requirements for heparan sulfate biosynthesis at the Drosophila neuromuscular junction: effects on synapse function, membrane trafficking, and mitochondrial localization.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9V730)
29. ensembl Release 106