# Topoisomerase (DNA) II alpha

> mammalian protein found in Mus musculus

**Wikidata**: [Q21989670](https://www.wikidata.org/wiki/Q21989670)  
**Source**: https://4ort.xyz/entity/topoisomerase-dna-ii-alpha


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q01320)
4. Q20641742
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
6. [Mutant isolation of mouse DNA topoisomerase II alpha in yeast](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
7. [Characterization of cDNA encoding the mouse DNA topoisomerase II that can complement the budding yeast top2 mutation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
8. [Analysis of expression and function of topoisomerase I and II during meiosis in male mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
9. [Modulation of topoisomerase activities by tumor necrosis factor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
10. [BAF complexes facilitate decatenation of DNA by topoisomerase IIα](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320)
12. [Condensin confers the longitudinal rigidity of chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320)
13. [Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320)
14. [Analysis of expression and function of topoisomerase I and II during meiosis in male mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01320&geneProductId=UniProtKB:Q01320)
15. [Condensins I and II are essential for construction of bivalent chromosomes in mouse oocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
16. [DNA topoisomerase II distribution in mouse preimplantation embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
17. [Cellular distribution of mammalian DNA topoisomerase II is determined by its catalytically dispensable C-terminal domain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
18. [Condensin confers the longitudinal rigidity of chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
20. [DNA topoisomerase II is essential for preimplantation mouse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
21. [Shikonin shortens the circadian period: possible involvement of Top2 inhibition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
22. [Haploinsufficiency of SAMD9L, an Endosome Fusion Facilitator, Causes Myeloid Malignancies in Mice Mimicking Human Diseases with Monosomy 7](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
23. [Possible role of DNA topoisomerase II on transcription of the homeobox gene Hox-2.1 in F9 embryonal carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01320)
24. ensembl Release 106