# Topoisomerase 2 Dmel_CG10223

> protein found in Drosophila melanogaster

**Wikidata**: [Q29810279](https://www.wikidata.org/wiki/Q29810279)  
**Source**: https://4ort.xyz/entity/topoisomerase-2-dmel-cg10223


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P15348)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
5. [Displacement of D1, HP1 and topoisomerase II from satellite heterochromatin by a specific polyamide](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
6. [Single-molecule analysis of DNA uncoiling by a type II topoisomerase.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
7. [Eukaryotic topoisomerases recognize nucleic acid topology by preferentially interacting with DNA crossovers](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
8. [During both interphase and mitosis, DNA topoisomerase II interacts with DNA as well as RNA through the protein's C-terminal domain.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
9. [Drosophila chromosome condensation proteins Topoisomerase II and Barren colocalize with Polycomb and maintain Fab-7 PRE silencing](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
10. [Single strand DNA cleavage reaction of duplex DNA by Drosophila topoisomerase II.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
11. [Drosophila CAP-D2 is required for condensin complex stability and resolution of sister chromatids](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
12. [Developmental regulation of DNA-topoisomerases during Drosophila embryogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
13. [Essential functions of DNA topoisomerase I in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
14. [Acf1, the largest subunit of CHRAC, regulates ISWI-induced nucleosome remodelling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
15. [Chromatin-remodelling factor CHRAC contains the ATPases ISWI and topoisomerase II.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
16. [ACF, an ISWI-Containing and ATP-Utilizing Chromatin Assembly and Remodeling Factor](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
17. [Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
18. [Condensin-dependent localisation of topoisomerase II to an axial chromosomal structure is required for sister chromatid resolution during mitosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
19. [RNAi analysis reveals an unexpected role for topoisomerase II in chromosome arm congression to a metaphase plate](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
20. [Spindle assembly and cytokinesis in the absence of chromosomes during Drosophila male meiosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
21. [A Genome-Wide RNAi Screen Identifies Core Components of the G 2 -M DNA Damage Checkpoint](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
22. [The NuRD nucleosome remodelling complex and NHK-1 kinase are required for chromosome condensation in oocytes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P15348&geneProductId=UniProtKB:P15348)
23. ensembl Release 106