# Toll-like receptor 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14907444](https://www.wikidata.org/wiki/Q14907444)  
**Source**: https://4ort.xyz/entity/toll-like-receptor-2-q14907444


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9QUN7)
3. Q20641742
4. [Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
5. [Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
7. [RING finger E3 ligase PPP1R11 regulates TLR2 signaling and innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
8. [Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
9. [Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
10. [A Mal functional variant is associated with protection against invasive pneumococcal disease, bacteremia, malaria and tuberculosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
11. [TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
12. [Dectin-1 mediates the biological effects of beta-glucans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
13. [NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
15. [TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
16. [The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
17. [Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
18. [Toll-like receptor 2 modulates the proinflammatory milieu in Staphylococcus aureus-induced brain abscess](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
19. [Nucleotide binding oligomerization domain 2 deficiency leads to dysregulated TLR2 signaling and induction of antigen-specific colitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
20. [CD36 is a sensor of diacylglycerides](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
21. [Cutting edge: TLR2-deficient and MyD88-deficient mice are highly susceptible to Staphylococcus aureus infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
22. [Critical role of NOD2 in regulating the immune response to Staphylococcus aureus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
23. [Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
24. [The cytosolic sensors Nod1 and Nod2 are critical for bacterial recognition and host defense after exposure to Toll-like receptor ligands](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
25. [GOA](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9QUN7)
26. [Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
27. [TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation](http://www.ebi.ac.uk/QuickGO/GAnnotation?protein=Q9QUN7)
28. [Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9QUN7)
29. ensembl Release 106