# Toll Dmel_CG5490

> protein found in Drosophila melanogaster

**Wikidata**: [Q29817352](https://www.wikidata.org/wiki/Q29817352)  
**Source**: https://4ort.xyz/entity/toll-dmel-cg5490


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08953)
3. Q20641742
4. [The polarisation of the anterior-posterior and dorsal-ventral axes during Drosophila oogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
5. [Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
6. [Drosophila MyD88 is an adapter in the Toll signaling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
7. [Drosophila MyD88 is required for the response to fungal and Gram-positive bacterial infections](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
8. [Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
9. [Structural insight into the mechanism of activation of the Toll receptor by the dimeric ligand Spätzle.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
10. [Toll gets tied in a knot](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
11. [An extracellular interactome of immunoglobulin and LRR proteins reveals receptor-ligand networks.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
12. [Multimerization and interaction of Toll and Spätzle in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
13. [Cytokine Spatzle binds to the Drosophila immunoreceptor Toll with a neurotrophin-like specificity and couples receptor activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
14. [Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
15. [Role of the Spatzle Pro-domain in the generation of an active toll receptor ligand](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
16. [Structure of the Toll-Spatzle complex, a molecular hub in Drosophila development and innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
18. [Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-kappaB morphogen gradient during Drosophila embryogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
19. [Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-kappaB morphogen gradient during Drosophila embryogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
20. [Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: importance of transmembrane signaling for dorsal-ventral pattern formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
21. [Mapping organelle proteins and protein complexes in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
22. [Plasma membrane polarity and compartmentalization are established before cellularization in the fly embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
23. [Endocytic pathway is required for Drosophila Toll innate immune signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
24. [Virus recognition by Toll-7 activates antiviral autophagy in Drosophila](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
26. [Plasma membrane localization of the Toll protein in the syncytial Drosophila embryo: importance of transmembrane signaling for dorsal-ventral pattern formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
28. [Mapping organelle proteins and protein complexes in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
29. [Interaction of the pelle kinase with the membrane-associated protein tube is required for transduction of the dorsoventral signal in Drosophila embryos](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
30. [Endocytic pathway is required for Drosophila Toll innate immune signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
31. [Plasma membrane polarity and compartmentalization are established before cellularization in the fly embryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
32. [Toll-deficient Drosophila is susceptible to Pythium insidiosum infection.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
33. [The antimicrobial host defense of Drosophila.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
34. [Toll we meet again....](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
35. [p38 MAPK signalling cascades: ancient roles and new functions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
36. [Drosophila host defense: differential induction of antimicrobial peptide genes after infection by various classes of microorganisms](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
37. [A mosaic analysis in Drosophila fat body cells of the control of antimicrobial peptide genes by the Rel proteins Dorsal and DIF.](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
38. [The immune response of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
39. [The ultrastructural interactions of identified pre- and postsynaptic cells during synaptic target recognition in Drosophila embryos.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
40. [Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
41. [TheTollPathway Is Required in the Epidermis for Muscle Development in theDrosophilaEmbryo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
42. [Flies kNOw how to signal](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
43. [The evolution and genetics of innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
44. [Fly immunity: great expectations](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
45. [Conservation and Divergence in Molecular Mechanisms of Axis Formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
46. [Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
47. [Weckle is a zinc finger adaptor of the toll pathway in dorsoventral patterning of the Drosophila embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
48. [Drosophila Tey represses transcription of the repulsive cue Toll and generates neuromuscular target specificity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08953)
49. [The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)
50. [Caenorhabditis elegans: an emerging genetic model for the study of innate immunity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08953&geneProductId=UniProtKB:P08953)