# TNF superfamily member 10

> mammalian protein found in Homo sapiens

**Wikidata**: [Q424394](https://www.wikidata.org/wiki/Q424394)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/TRAIL)  
**Source**: https://4ort.xyz/entity/tnf-superfamily-member-10


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P50591)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
6. [Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
7. [Inhibition of vacuolar ATPase attenuates the TRAIL-induced activation of caspase-8 and modulates the trafficking of TRAIL receptosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
8. [Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
9. [Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
10. [Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
11. [Triggering cell death: the crystal structure of Apo2L/TRAIL in a complex with death receptor 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
12. [Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
13. [Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
14. [Multivalent DR5 peptides activate the TRAIL death pathway and exert tumoricidal activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
15. [Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
16. [Identification and characterization of a new member of the TNF family that induces apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
17. [The structure of the death receptor 4–TNF-related apoptosis-inducing ligand (DR4–TRAIL) complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50591&geneProductId=UniProtKB:P50591)
19. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?protein=P50591&geneProductId=UniProtKB:P50591)
20. [Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
21. [Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
22. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P50591)
23. Ensembl Release 99
24. Identifiers.org
25. UMLS 2023