# TNF receptor associated factor 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21173526](https://www.wikidata.org/wiki/Q21173526)  
**Source**: https://4ort.xyz/entity/tnf-receptor-associated-factor-3


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13114)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
5. [A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13114&geneProductId=UniProtKB:Q13114)
6. [Involvement of CRAF1, a relative of TRAF, in CD40 signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13114&geneProductId=UniProtKB:Q13114)
7. [Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
8. [The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
9. [The tyrosine kinase c-Src enhances RIG-I (retinoic acid-inducible gene I)-elicited antiviral signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
10. [Downstream regulator TANK binds to the CD40 recognition site on TRAF3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
11. [MIP-T3, a novel protein linking tumor necrosis factor receptor-associated factor 3 to the microtubule network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
12. [Mapping a dynamic innate immunity protein interaction network regulating type I interferon production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
13. [The autoimmunity-associated gene PTPN22 potentiates toll-like receptor-driven, type 1 interferon-dependent immunity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
14. [Identification and characterization of receptor-interacting protein 2 as a TNFR-associated factor 3 binding partner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
15. [BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
16. [A novel RING finger protein interacts with the cytoplasmic domain of CD40](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
17. [A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
18. [Using an in Situ Proximity Ligation Assay to Systematically Profile Endogenous Protein–Protein Interactions in a Pathway Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
19. [WDR5 is essential for assembly of the VISA-associated signaling complex and virus-triggered IRF3 and NF-kappaB activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
20. [Relief of Profound Feedback Inhibition of Mitogenic Signaling by RAF Inhibitors Attenuates Their Activity in BRAFV600E Melanomas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
21. [Role of TRAF3 and -6 in the activation of the NF-kappa B and JNK pathways by X-linked ectodermal dysplasia receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
22. [A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
23. [A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13114&geneProductId=UniProtKB:Q13114)
24. [A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13114&geneProductId=UniProtKB:Q13114)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13114&geneProductId=UniProtKB:Q13114)
26. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
27. [A Novel TNF Receptor Family Member Binds TWEAK and Is Implicated in Angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
28. [TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13114&geneProductId=UniProtKB:Q13114)
29. [The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
30. [A novel member of the TRAF family of putative signal transducing proteins binds to the cytosolic domain of CD40](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
31. [TRAF3 controls activation of the canonical and alternative NFkappaB by the lymphotoxin beta receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13114)
32. Ensembl Release 99