# TNF receptor-associated factor 2

> mammalian protein found in Mus musculus

**Wikidata**: [Q14914363](https://www.wikidata.org/wiki/Q14914363)  
**Source**: https://4ort.xyz/entity/tnf-receptor-associated-factor-2-q14914363


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P39429)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
5. [HOIL-1L Interacting Protein (HOIP) as an NF-κB Regulating Component of the CD40 Signaling Complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
6. [The TNF receptor family member CD27 signals to Jun N-terminal kinase via Traf-2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
7. [FLN29 Deficiency Reveals Its Negative Regulatory Role in the Toll-like Receptor (TLR) and Retinoic Acid-inducible Gene I (RIG-I)-like Helicase Signaling Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
8. [Caspase‐8 and caspase‐10 activate NF‐κB through RIP, NIK and IKKα kinases](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
9. [AIP1 Is Critical in Transducing IRE1-mediated Endoplasmic Reticulum Stress Response](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
10. [Suppressive effect of reactive oxygen species on CD40‐induced B cell activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
11. [Bioinformatics and cellular signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
12. [4-1BB and Ox40 Are Members of a Tumor Necrosis Factor (TNF)-Nerve Growth Factor Receptor Subfamily That Bind TNF Receptor-Associated Factors and Activate Nuclear Factor κB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
13. [T cells down-regulate macrophage TNF production by IRAK1-mediated IL-10 expression and control innate hyperinflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
14. [The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
15. [Antigen-independent signalosome of CARMA1, PKCθ, and TNF receptor-associated factor 2 (TRAF2) determines NF-κB signaling in T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
16. [Nonstructural 5A Protein of Hepatitis C Virus Modulates Tumor Necrosis Factor α-stimulated Nuclear Factor κB Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
17. [Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
18. [The RET/PTC3 oncogene activates classical NF-κB by stabilizing NIK](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
19. [The kinase IKKα inhibits activation of the transcription factor NF-κB by phosphorylating the regulatory molecule TAX1BP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
20. [OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
21. [Hepatitis C Virus Core Protein Potentiates TNF-α-Induced NF-κB Activation through TRAF2-IKKβ-Dependent Pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
22. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
24. [The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
25. [ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429)
26. [Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429)
27. [The zinc finger protein A20 targets TRAF2 to the lysosomes for degradation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429)
28. [Signaling pathways from membrane lipid rafts to JNK1 activation in reactive nitrogen species-induced non-apoptotic cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
29. [ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
30. [Tumor Necrosis Factor Receptor-associated Factor 2 (TRAF2)-deficient B Lymphocytes Reveal Novel Roles for TRAF2 in CD40 Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
31. [TRAF Family Proteins Link PKR with NF-κB Activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429)
32. [Hepatitis C Virus Core Protein Potentiates TNF-α-Induced NF-κB Activation through TRAF2-IKKβ-Dependent Pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=P39429&geneProductId=UniProtKB:P39429)
33. [TRAF Family Proteins Link PKR with NF-κB Activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P39429)
34. ensembl Release 106