# TIAM Rac1 associated GEF 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21123942](https://www.wikidata.org/wiki/Q21123942)  
**Source**: https://4ort.xyz/entity/tiam-rac1-associated-gef-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q13009)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
5. [Tiam1 Regulates the Wnt/Dvl/Rac1 Signaling Pathway and the Differentiation of Midbrain Dopaminergic Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
6. [The Structure of the Tiam1 PDZ Domain/ Phospho-Syndecan1 Complex Reveals a Ligand Conformation that Modulates Protein Dynamics](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
7. [The Rac1 guanine nucleotide exchange factor Tiam1 mediates EphB receptor-dependent dendritic spine development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13009&geneProductId=UniProtKB:Q13009)
9. [The Rac1-GEF Tiam1 Couples the NMDA Receptor to the Activity-Dependent Development of Dendritic Arbors and Spines](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q13009&geneProductId=UniProtKB:Q13009)
10. [The Rac1-GEF Tiam1 Couples the NMDA Receptor to the Activity-Dependent Development of Dendritic Arbors and Spines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
11. [CCM1 regulates vascular-lumen organization by inducing endothelial polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
12. [The Tiam1 PDZ Domain Couples to Syndecan1 and Promotes Cell–Matrix Adhesion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
13. [Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
14. [miR-29b suppresses tumor growth and metastasis in colorectal cancer via downregulating Tiam1 expression and inhibiting epithelial–mesenchymal transition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
15. [miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
16. [Tiam1 regulates cell adhesion, migration and apoptosis in colon tumor cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q13009)
17. Ensembl Release 99