# Thyroid hormone receptor alpha

> mammalian protein found in Mus musculus

**Wikidata**: [Q21986929](https://www.wikidata.org/wiki/Q21986929)  
**Source**: https://4ort.xyz/entity/thyroid-hormone-receptor-alpha-q21986929


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P63058)
3. Q20641742
4. [Characterization of a novel thyroid hormone receptor alpha variant involved in the regulation of myoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
5. [An RNA-binding domain in the thyroid hormone receptor enhances transcriptional activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
8. [The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
9. [TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
10. [The mammalian clock component PERIOD2 coordinates circadian output by interaction with nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
11. [TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
12. [The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
13. [Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
14. [Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
15. [The c-erb-A gene encodes a thyroid hormone receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
16. [Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
17. [The frizzled-related sFRP2 gene is a target of thyroid hormone receptor alpha1 and activates beta-catenin signaling in mouse intestine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
19. [The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
21. [The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
22. [Neurological defects in trichothiodystrophy reveal a coactivator function of TFIIH](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
23. [Characterization of a novel thyroid hormone receptor alpha variant involved in the regulation of myoblast differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
24. [Erythroid defects in TRalpha-/- mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
25. [Abnormal heart rate and body temperature in mice lacking thyroid hormone receptor alpha 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
26. [Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
27. [Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
28. [The two thyroid hormone receptor genes have opposite effects on estrogen-stimulated sex behaviors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
29. [Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
30. [A thyroid hormone receptor alpha gene mutation (P398H) is associated with visceral adiposity and impaired catecholamine-stimulated lipolysis in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
31. [Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
32. [Behavioral inhibition and impaired spatial learning and memory in hypothyroid mice lacking thyroid hormone receptor alpha](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
33. [Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
34. [Mixed lineage kinase 2 enhances trans-repression of Alien and nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
35. [Structural and functional organization of TRAP220, the TRAP/mediator subunit that is targeted by nuclear receptors](http://www.ebi.ac.uk/QuickGO/annotations?protein=P63058&geneProductId=UniProtKB:P63058)
36. [Congenital hypothyroid Pax8(-/-) mutant mice can be rescued by inactivating the TRalpha gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
37. [Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
38. [Type-2 iodothyronine 5'deiodinase (D2) in skeletal muscle of C57Bl/6 mice. II. Evidence for a role of D2 in the hypermetabolism of thyroid hormone receptor alpha-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P63058)
39. ensembl Release 106