# Thymoma viral proto-oncogene 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q21498923](https://www.wikidata.org/wiki/Q21498923)  
**Source**: https://4ort.xyz/entity/thymoma-viral-proto-oncogene-1


## References

1. UniProt
2. Q20641742
3. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
4. [KCTD20, a relative of BTBD10, is a positive regulator of Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
5. [Phosphorylation of grb10 regulates its interaction with 14-3-3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
6. [A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
7. [A novel protein kinase B (PKB)/AKT-binding protein enhances PKB kinase activity and regulates DNA synthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
8. [A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
9. [Akt phosphorylates and regulates Pdcd4 tumor suppressor protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
10. [An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
11. [ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
12. [ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
13. [BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
14. [Identification and characterization of a novel gene, dapr, involved in skeletal muscle differentiation and protein kinase B signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
15. [TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
16. [Ack1 mediated AKT/PKB tyrosine 176 phosphorylation regulates its activation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
17. [PML regulates apoptosis at endoplasmic reticulum by modulating calcium release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
18. [Bag1 is essential for differentiation and survival of hematopoietic and neuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
19. [Protein kinase N1, a cell inhibitor of Akt kinase, has a central role in quality control of germinal center formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
20. [Akt augments the oncogenic potential of the HBx protein of hepatitis B virus by phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
21. [Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
22. [Selective activation of Akt1 by mammalian target of rapamycin complex 2 regulates cancer cell migration, invasion, and metastasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
23. [The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
24. [Evidence for the involvement of FAM110C protein in cell spreading and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
25. [ZNRF2 is released from membranes by growth factors and, together with ZNRF1, regulates the Na+/K+ATPase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
26. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
27. [Akt phosphorylates and regulates Pdcd4 tumor suppressor protein](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
28. [The costimulation-regulated duration of PKB activation controls T cell longevity](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
29. [Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
30. [IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
31. [PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
32. [Regulation of apoptosis by the Ft1 protein, a new modulator of protein kinase B/Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
33. [Insulin-induced phosphorylation and activation of cyclic nucleotide phosphodiesterase 3B by the serine-threonine kinase Akt](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
34. [ZNRF1 promotes Wallerian degeneration by degrading AKT to induce GSK3B-dependent CRMP2 phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
35. [The protooncogene TCL1 is an Akt kinase coactivator](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
36. [Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P31750&geneProductId=UniProtKB:P31750)
37. [The costimulation-regulated duration of PKB activation controls T cell longevity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
38. [PS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
39. [IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
40. [The protooncogene TCL1 is an Akt kinase coactivator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
41. [Oct4 interaction with Hmgb2 regulates Akt signaling and pluripotency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
42. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
43. [Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
44. [The role of Asp-462 in regulating Akt activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
45. [Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
46. [Growth arrest induces primary-cilium formation and sensitizes IGF-1-receptor signaling during differentiation induction of 3T3-L1 preadipocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
47. [The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
48. [Nonredundant role of Akt2 for neuroprotection of rod photoreceptor cells from light-induced cell death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
49. [External push and internal pull forces recruit curvature-sensing N-BAR domain proteins to the plasma membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)
50. [E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P31750)