# Thymidylate synthetase

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561458](https://www.wikidata.org/wiki/Q28561458)  
**Source**: https://4ort.xyz/entity/thymidylate-synthetase-q28561458


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P45352)
3. Q20641742
4. [Crystal structures of rat thymidylate synthase inhibited by Tomudex, a potent anticancer drug](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
6. [Thymidylate synthase protein and p53 mRNA form an in vivo ribonucleoprotein complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
7. [Simultaneous measurement of one-carbon and polyglutamate derivatives of folic acid in rat liver using enzymatic interconversions of folates followed by ternary complex formation with thymidylate synthetase and 5-fluorodeoxyuridylic acid: standardiza](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
8. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
9. [Intracellular location of thymidylate synthase and its state of phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
10. [5-Fluorocytosine-mediated apoptosis and DNA damage in glioma cells engineered to express cytosine deaminase and their enhancement with interferon](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
11. [Properties of phosphorylated thymidylate synthase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
12. [Thymidylate synthetase and thymidine kinase activities in rat growing cartilage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
13. [Circadian variation in intestinal dihydropyrimidine dehydrogenase (DPD) expression: a potential mechanism for benefits of 5FU chrono-chemotherapy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
14. [Inhibition of thymidylate synthase and thymidine kinase by okadaic acid in regenerating rat liver after partial hepatectomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
15. [Protective effects of an antiulcer agent, ecabet sodium on colorectal carcinogenesis in rodents](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
16. [The effects of fluorouracil on thymidylate synthase and thymidine kinase in regenerating rat liver after partial hepatectomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
17. [Additive effects of medroxyprogesterone acetate and 5-fluorouracil derivative on 7,12-dimethylbenz-[a]anthracene-induced rat mammary tumors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
18. [Retinoic acid repressed the expression of c-fos and c-jun and induced apoptosis in regenerating rat liver after partial hepatectomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
19. [Does macrophage-colony stimulating factor stimulate rat haematopoietic cells?](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
20. [Ethanol represses thymidylate synthase and thymidine kinase at mRNA level in regenerating rat liver after partial hepatectomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
21. [Antitumour effects of pure diastereoisomers of 5-formyltetrahydrofolate in hepatic transplants of a rodent colon carcinoma model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
22. [Relative activities of thymidylate synthetase and thymidine kinase in rat tissues](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
23. [Effect of glucocorticoid on liver regeneration after partial hepatectomy in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
24. [Effect of folic acid on thymidylate synthase and thymidine kinase in regenerating rat liver after partial hepatectomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
25. [Differentiation associated changes in thymidylate synthetase and thymidine kinase activities in intestinal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P45352)
26. ensembl Release 106