# Thioredoxin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q421219](https://www.wikidata.org/wiki/Q421219)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Thioredoxin)  
**Source**: https://4ort.xyz/entity/thioredoxin


## References

1. UniProt
2. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL406050)
3. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P10599)
4. Q20641742
5. Freebase Data Dumps. 2013
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
7. [Salmonella type III secretion effector SlrP is an E3 ubiquitin ligase for mammalian thioredoxin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
8. [Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
9. [Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
10. [Positive Regulation of Apoptosis Signal-regulating Kinase 1 Signaling by ZPR9 Protein, a Zinc Finger Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
11. [A possible interaction of thioredoxin with VDUP1 in HeLa cells detected in a yeast two-hybrid system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
12. [The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
13. [Thioredoxin modulates activator protein 1 (AP-1) activity and p27Kip1 degradation through direct interaction with Jab1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
14. [CIB1 functions as a Ca(2+)-sensitive modulator of stress-induced signaling by targeting ASK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
15. [Toward an understanding of the protein interaction network of the human liver](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
16. [Thioredoxin is required for S-nitrosation of procaspase-3 and the inhibition of apoptosis in Jurkat cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
17. [Selective redox regulation of cytokine receptor signaling by extracellular thioredoxin-1.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
18. [Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
19. [Reactivation of oxidized PTP1B and PTEN by thioredoxin 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
20. [Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
21. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
22. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
23. [The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
24. [Insights into RNA biology from an atlas of mammalian mRNA-binding proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
25. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
26. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
27. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
28. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
29. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=P10599&geneProductId=UniProtKB:P10599)
30. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
31. [Large-scale proteomics and phosphoproteomics of urinary exosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
32. [In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
33. [DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
34. [Trafficking of neutrophils across airway epithelium is dependent upon both thioredoxin- and pertussis toxin-sensitive signaling mechanisms](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
35. [Cloning and expression of a cDNA for human thioredoxin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P10599)
36. Ensembl Release 99
37. Identifiers.org
38. Quora
39. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)