# thioredoxin reductase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21106751](https://www.wikidata.org/wiki/Q21106751)  
**Source**: https://4ort.xyz/entity/thioredoxin-reductase-1-q21106751


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q16881)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16881&geneProductId=UniProtKB:Q16881)
6. [An Alternative Splicing Variant of the Selenoprotein Thioredoxin Reductase Is a Modulator of Estrogen Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
7. [Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress‐induced premature senescence](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
8. [Human thioredoxin reductase from HeLa cells: Selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16881&geneProductId=UniProtKB:Q16881)
9. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16881&geneProductId=UniProtKB:Q16881)
10. [Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16881&geneProductId=UniProtKB:Q16881)
11. [Human thioredoxin reductase from HeLa cells: Selective alkylation of selenocysteine in the protein inhibits enzyme activity and reduction with NADPH influences affinity to heparin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
13. [Proteomic Analysis of Exosomes from Human Neural Stem Cells by Flow Field-Flow Fractionation and Nanoflow Liquid Chromatography−Tandem Mass Spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q16881&geneProductId=UniProtKB:Q16881)
14. [Proteomic Analysis of Exosomes from Human Neural Stem Cells by Flow Field-Flow Fractionation and Nanoflow Liquid Chromatography−Tandem Mass Spectrometry](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
15. [Human Thioredoxin Reductase Gene Localization to Chromosomal Position 12q23–q24.1 and mRNA Distribution in Human Tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q16881)
16. Ensembl Release 99
17. UMLS 2023