# The Target Trial Framework for Causal Inference From Observational Data: Why and When Is It Helpful?

> Research article (Annals of Internal Medicine, 2025) · cited 120× · AI/ML

**Wikidata**: [openalex:W4407671601](https://www.wikidata.org/wiki/openalex:W4407671601)  
**Source**: https://4ort.xyz/entity/the-target-trial-framework-for-causal-inference-from-observational-data-why-and-when-is-it-helpful