# THAP domain containing 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21172844](https://www.wikidata.org/wiki/Q21172844)  
**Source**: https://4ort.xyz/entity/thap-domain-containing-1-q21172844


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9NVV9)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
5. [Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
6. [The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
7. [Structure-Function Analysis of the THAP Zinc Finger of THAP1, a Large C2CH DNA-binding Module Linked to Rb/E2F Pathways](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
8. [THAP proteins target specific DNA sites through bipartite recognition of adjacent major and minor grooves](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
9. [The THAP–zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
10. [The THAP-Zinc Finger Protein THAP1 Associates with Coactivator HCF-1 and O-GlcNAc Transferase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
11. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
12. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
13. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
14. [Widespread Macromolecular Interaction Perturbations in Human Genetic Disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
15. [Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NVV9&geneProductId=UniProtKB:Q9NVV9)
17. [In-depth Characterization of the Homodimerization Domain of the Transcription Factor THAP1 and Dystonia-Causing Mutations Therein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
18. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
19. [The THAP–zinc finger protein THAP1 regulates endothelial cell proliferation through modulation of pRB/E2F cell-cycle target genes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9NVV9&geneProductId=UniProtKB:Q9NVV9)
20. [The dystonia gene DYT1 is repressed by the transcription factor THAP1 (DYT6)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NVV9)
21. Ensembl Release 99