# Teunissen–Cremers syndrome

> Stapes ankylosis with broad thumbs and toes is a very rare genetic bone disorder characterized by ankylosis of stapes, broad thumbs and halluces, conductive hearing loss and hyperopia

**Wikidata**: [Q7707070](https://www.wikidata.org/wiki/Q7707070)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Teunissen–Cremers_syndrome)  
**Source**: https://4ort.xyz/entity/teunissen-cremers-syndrome


## References

1. Monarch Disease Ontology release 2018-06-29
2. UniProt
3. Autosomal dominant stapes ankylosis with broad thumbs and toes, hyperopia, and skeletal anomalies is caused by heterozygous nonsense and frameshift mutations in NOG, the gene encoding noggin
4. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000183691/MONDO_0008484)