# TBX3

> protein-coding gene in the species Homo sapiens

**Wikidata**: [Q18031866](https://www.wikidata.org/wiki/Q18031866)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/TBX3)  
**Source**: https://4ort.xyz/entity/tbx3


## References

1. ensembl Release 106
2. Ensembl Release 87
3. Q20641742
4. Online Mendelian Inheritance in Man
5. HomoloGene build68
6. [Orthologous MAtrix](https://omabrowser.org/oma/vps/O15119/)
7. UniProt
8. Functional identity of hypothalamic melanocortin neurons depends on Tbx3
9. The roles and regulation of TBX3 in development and disease.
10. The T-box transcription factor 3 is a promising biomarker and a key regulator of the oncogenic phenotype of a diverse range of sarcoma subtypes
11. TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases
12. Tbx3 overexpression in human gastric cancer is correlated with advanced tumor stage and nodal status and promotes cancer cell growth and invasion
13. Tbx3 represses PTEN and is over-expressed in head and neck squamous cell carcinoma
14. Expression of TBX3 in Hepatocellular Carcinoma and Its Clinical Implication
15. T-box 3 overexpression is associated with poor prognosis of non-small cell lung cancer
16. The T-box transcription factor, TBX3, is sufficient to promote melanoma formation and invasion
17. Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients
18. Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness
19. Overexpression of Tbx3 is correlated with Epithelial-Mesenchymal Transition phenotype and predicts poor prognosis of colorectal cancer
20. Mutations in human TBX3 alter limb, apocrine and genital development in ulnar-mammary syndrome
21. A new PKCα/β/TBX3/E-cadherin pathway is involved in PLCε-regulated invasion and migration in human bladder cancer cells
22. [Phenocarta](https://gemma.msl.ubc.ca/phenotypes.html?phenotypeUrlId=DOID_9256&ncbiId=6926)
23. [Open Targets Platform](https://platform.opentargets.org/evidence/ENSG00000135111/MONDO_0008411)
24. [Identifiers.org](http://www.ebi.ac.uk/miriam/main/collections/MIR:00000069)
25. UMLS 2023
26. [Bgee](https://www.bgee.org/gene/ENSG00000135111)