TBC1 domain family member 7
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P637
  value: NP_001137436
additional property: PropertyValue
  property ID: P637
  value: NP_001137437
additional property: PropertyValue
  property ID: P637
  value: NP_001137438
additional property: PropertyValue
  property ID: P638
  value: 3QWL
additional property: PropertyValue
  property ID: P638
  value: 5EJC
additional property: PropertyValue
  property ID: P638
  value: 4Z6Y
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: GTPase activator activity
additional property: PropertyValue
  property ID: P680
  value: GTPase activator activity
additional property: PropertyValue
  property ID: P681
  value: ciliary basal body
additional property: PropertyValue
  property ID: P681
  value: cytoplasmic vesicle
additional property: PropertyValue
  property ID: P681
  value: cytosol
additional property: PropertyValue
  property ID: P682
  value: negative regulation of TOR signaling
additional property: PropertyValue
  property ID: P682
  value: response to growth factor
additional property: PropertyValue
  property ID: P682
  value: positive regulation of protein ubiquitination
additional property: PropertyValue
  property ID: P702
  value: TBC1D7
additional property: PropertyValue
  property ID: P702
  value: TBC1D7-LOC100130357
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000343100
additional property: PropertyValue
  property ID: P705
  value: ENSP00000348813
additional property: PropertyValue
  property ID: P705
  value: ENSP00000368602
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 14
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 14
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: Q9P0N9
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001137436
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001137437
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001137438
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001245386
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001305734
    source count: 1
    confidence: 0.2
  P638:
    value: 3QWL
    source count: 1
    confidence: 0.2
  P638:
    value: 5EJC
    source count: 1
    confidence: 0.2
  P638:
    value: 4Z6Y
    source count: 1
    confidence: 0.2
  P680:
    value: Q167149
    source count: 4
    confidence: 0.8
    value label: protein binding
  P680:
    value: Q14908102
    source count: 2
    confidence: 0.4
    value label: GTPase activator activity
  P680:
    value: Q14908102
    source count: 3
    confidence: 0.6
    value label: GTPase activator activity
  P681:
    value: Q21096453
    source count: 1
    confidence: 0.2
    value label: ciliary basal body
  P681:
    value: Q14840128
    source count: 2
    confidence: 0.4
    value label: cytoplasmic vesicle
  P681:
    value: Q220599
    source count: 1
    confidence: 0.2
    value label: cytosol
  P682:
    value: Q14908110
    source count: 2
    confidence: 0.4
    value label: negative regulation of TOR signaling
  P682:
    value: Q14866110
    source count: 1
    confidence: 0.2
    value label: response to growth factor
  P682:
    value: Q14860454
    source count: 1
    confidence: 0.2
    value label: positive regulation of protein ubiquitination
  P682:
    value: Q21103268
    source count: 1
    confidence: 0.2
    value label: negative regulation of cilium assembly
  P682:
    value: Q21095706
    source count: 2
    confidence: 0.4
    value label: activation of GTPase activity
  P702:
    value: Q18040129
    source count: 1
    confidence: 0.2
    value label: TBC1D7
  P702:
    value: Q24289756
    source count: 1
    confidence: 0.2
    value label: TBC1D7-LOC100130357
  P703:
    value: Q15978631
    source count: 1
    confidence: 0.2
    value label: Homo sapiens
  P705:
    value: ENSP00000343100
    source count: 1
    confidence: 0.2

value: ENSP00000348813
source count: 1
confidence: 0.2

value: ENSP00000368602
source count: 1
confidence: 0.2

value: ENSP00000368609
source count: 1
confidence: 0.2

value: ENSP00000475727
source count: 1
confidence: 0.2

source: Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers
stated in qid: Q24305592
retrieved: 2019-04-08

source: Identification of TBC7 having TBC domain as a novel binding protein to TSC1-TSC2 complex
stated in qid: Q24322703
retrieved: 2019-04-08

source: A proteome-scale map of the human interactome network
stated in qid: Q24307146
retrieved: 2019-04-08

source: Pooled-matrix protein interaction screens using Barcode Fusion Genetics
stated in qid: Q28114947
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-06-05

source: Functional dissection of Rab GTPases involved in primary cilium formation
stated in qid: Q24321757
retrieved: 2018-06-05

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Functional dissection of Rab GTPases involved in primary cilium formation
stated in qid: Q24321757
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
stated in qid: Q24293153
retrieved: 2018-06-05

source: TBC1D7 Is a Third Subunit of the TSC1-TSC2 Complex Upstream of mTORC1
stated in qid: Q24293153
retrieved: 2019-04-08

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-04-04

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21103269
domain: protein
level: standard
html url: https://4ort.xyz/entity/tbc1-domain-family-member-7-q21103269
markdown url: https://4ort.xyz/entity/tbc1-domain-family-member-7-q21103269.md
facts url summary: https://4ort.xyz/entity/tbc1-domain-family-member-7-q21103269/facts.json
facts url standard: https://4ort.xyz/entity/tbc1-domain-family-member-7-q21103269/facts.json
facts url full: https://4ort.xyz/entity/tbc1-domain-family-member-7-q21103269/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-01T19:12:12.074920Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:25:56.647217+00:00Z