TATA-box binding protein
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P20226
additional property: PropertyValue
  property ID: P361
  value: TATA-box binding protein, eukaryotic
additional property: PropertyValue
  property ID: P361
  value: TBP domain superfamily
additional property: PropertyValue
  property ID: P361
  value: TATA-box binding protein, conserved site, protein family
additional property: PropertyValue
  property ID: P527
  value: TATA-box binding protein, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_001165556
additional property: PropertyValue
  property ID: P637
  value: NP_003185
additional property: PropertyValue
  property ID: P638
  value: 1TGH
additional property: PropertyValue
  property ID: P638
  value: 1C9B
additional property: PropertyValue
  property ID: P638
  value: 1JFI
additional property: PropertyValue
  property ID: P646
  value: /m/09041g
additional property: PropertyValue
  property ID: P680
  value: DNA binding
additional property: PropertyValue
  property ID: P680
  value: DNA-binding transcription factor activity
additional property: PropertyValue
  property ID: P680
  value: transcription factor binding
additional property: PropertyValue
  property ID: P681
  value: cytoplasm
additional property: PropertyValue
  property ID: P681
  value: transcription factor TFIID complex
additional property: PropertyValue
  property ID: P681
  value: male pronucleus
additional property: PropertyValue
  property ID: P682
  value: termination of RNA polymerase I transcription
additional property: PropertyValue
  property ID: P682
  value: epigenetic maintenance of chromatin in transcription-competent conformation
additional property: PropertyValue
  property ID: P682
  value: regulation of transcription, DNA-templated
additional property: PropertyValue
  property ID: P692
  value: PBB GE TBP 203135 at fs.png
additional property: PropertyValue
  property ID: P702
  value: TBP
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000442132
additional property: PropertyValue
  property ID: P705
  value: ENSP00000230354
additional property: PropertyValue
  property ID: P705
  value: ENSP00000375942
additional property: PropertyValue
  property ID: P2892
  value: C0144555
confidence:
  popularity graph score:
    score: 0.009
    score pct: 1
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 64
      unique citations norm: 0.025
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 64
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P20226
    source count: 1
    confidence: 0.2
  P361:
    value: Q24744898
    source count: 1
    confidence: 0.2
    value label: TATA-box binding protein, eukaryotic
  P361:
    value: Q54450308
    source count: 1
    confidence: 0.2
    value label: TBP domain superfamily
  P361:
    value: Q95354654
    source count: 1
    confidence: 0.2
    value label: TATA-box binding protein, conserved site, protein family
  P527:
    value: Q24774957
    source count: 1
    confidence: 0.2
    value label: TATA-box binding protein, conserved site
  P637:
    value: NP_001165556
    source count: 1
    confidence: 0.2
  P637:
    value: NP_003185
    source count: 1
    confidence: 0.2
  P638:
    value: 1TGH
    source count: 1
    confidence: 0.2
  P638:
    value: 1C9B
    source count: 1
    confidence: 0.2
  P638:
    value: 1JFI
    source count: 1
    confidence: 0.2
  P638:
    value: 1NVP
    source count: 1
    confidence: 0.2
  P638:
    value: 4ROC
    source count: 1
    confidence: 0.2
  P646:
    value: /m/09041g
    source count: 1
    confidence: 0.2
  P680:
    value: Q14633858
    source count: 3
    confidence: 0.6
    value label: DNA binding
  P680:
    value: Q14817979
    source count: 1
    confidence: 0.2
    value label: DNA-binding transcription factor activity
  P680:
    value: Q14817982
    source count: 5
    confidence: 1.0
    value label: transcription factor binding
  P680:
    value: Q14885806
    source count: 1
    confidence: 0.2
    value label: RNA polymerase II cis-regulatory region sequence-specific DNA binding
  P680:
    value: Q167149
    source count: 35
    confidence: 1.0
    value label: protein binding
  P681:
    value: Q79899
    source count: 1
    confidence: 0.2
    value label: cytoplasm
  P681:
    value: Q14817959
    source count: 6
    confidence: 1.0
    value label: transcription factor TFIID complex
  P681:
    value: Q14878254
    source count: 1
    confidence: 0.2
    value label: male pronucleus

value: Q14878252
source count: 1
confidence: 0.2
value label: female pronucleus

value: Q14817956
source count: 2
confidence: 0.4
value label: nucleoplasm

value: Q14908090
source count: 1
confidence: 0.2
value label: termination of RNA polymerase I transcription

value: Q21105906
source count: 1
confidence: 0.2
value label: epigenetic maintenance of chromatin in transcription-competent conformation

value: Q14633883
source count: 1
confidence: 0.2
value label: regulation of transcription, DNA-templated

value: Q14908088
source count: 1
confidence: 0.2
value label: transcription initiation from RNA polymerase I promoter

value: Q14763010
source count: 1
confidence: 0.2
value label: transcription, DNA-templated

value: PBB GE TBP 203135 at fs.png
source count: 0
confidence: 0.0

value: Q14878262
source count: 1
confidence: 0.2
value label: TBP

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000442132
source count: 1
confidence: 0.2

value: ENSP00000230354
source count: 1
confidence: 0.2

value: ENSP00000375942
source count: 1
confidence: 0.2

value: ENSP00000400008
source count: 1
confidence: 0.2

value: ENSP00000404905
source count: 1
confidence: 0.2

value: C0144555
source count: 1
confidence: 0.2

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-07-16

source: Potential targets for HSF1 within the preinitiation complex
stated in qid: Q24290312
retrieved: 2018-07-16

source: TAF7 (TAFII55) plays a role in the transcription activation by c-Jun
stated in qid: Q24299340
retrieved: 2018-07-16

source: The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIB
stated in qid: Q24309276
retrieved: 2018-07-16

source: Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
stated in qid: Q24315678
retrieved: 2018-07-16

source: Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding
stated in qid: Q24310214
retrieved: 2018-07-16

source: Structural basis of preinitiation complex assembly on human pol II promoters
stated in qid: Q27620858
retrieved: 2019-04-08

source: The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein
stated in qid: Q24311826
retrieved: 2019-04-08

source: Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis
stated in qid: Q24306288
retrieved: 2019-04-08

source: The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger
stated in qid: Q24291405
retrieved: 2019-04-08

source: Characterization of Functional Domains of an Embryonic Stem Cell Coactivator UTF1 Which Are Conserved and Essential for Potentiation of ATF-2 Activity
stated in qid: Q24315929
retrieved: 2019-04-08

source: Evolutionary conservation of human TATA-binding-polypeptide-associated factors TAFII31 and TAFII80 and interactions of TAFII80 with other TAFs and with general transcription factors
stated in qid: Q24337254
retrieved: 2019-04-08

source: Exon 4-encoded acidic domain in the epithelium-restricted Ets factor, ESX, confers potent transactivating capacity and binds to TATA-binding protein (TBP)
stated in qid: Q22010203
retrieved: 2019-04-08

source: Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID
stated in qid: Q24315758
retrieved: 2019-04-08

source: Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.
stated in qid: Q38318608
retrieved: 2019-04-08

source: Cloning and expression of human TAFII250: a TBP-associated factor implicated in cell-cycle regulation
stated in qid: Q24308057
retrieved: 2019-04-08

source: Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism
stated in qid: Q24298601
retrieved: 2019-04-08

source: Wild-type p53 binds to the TATA-binding protein and represses transcription
stated in qid: Q24300991
retrieved: 2019-04-08

source: Specific interactions and potential functions of human TAFII100
stated in qid: Q24322534
retrieved: 2019-04-08

source: Domains of Brn-2 that mediate homodimerization and interaction with general and melanocytic transcription factors
stated in qid: Q24290395
retrieved: 2019-04-08

source: The role of human MBF1 as a transcriptional coactivator
stated in qid: Q22010815
retrieved: 2019-04-08

source: The equine herpesvirus 1 EICP27 protein enhances gene expression via an interaction with TATA box-binding protein
stated in qid: Q28117137
retrieved: 2019-04-08

source: Human general transcription factor TFIIA: characterization of a cDNA encoding the small subunit and requirement for basal and activated transcription
stated in qid: Q24315678
retrieved: 2019-04-08

source: Identification of novel functional TBP-binding sites and general factor repertoires
stated in qid: Q24295026
retrieved: 2019-04-08

source: Interaction of the equine herpesvirus 1 EICP0 protein with the immediate-early (IE) protein, TFIIB, and TBP may mediate the antagonism between the IE and EICP0 proteins
stated in qid: Q28115197
retrieved: 2019-04-08

source: Two domains of p53 interact with the TATA-binding protein, and the adenovirus 13S E1A protein disrupts the association, relieving p53-mediated transcriptional repression
stated in qid: Q24336035
retrieved: 2019-04-08

source: A human interactome in three quantitative dimensions organized by stoichiometries and abundances
stated in qid: Q27936244
retrieved: 2019-04-08

source: Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA binding
stated in qid: Q24310214
retrieved: 2019-04-08

source: TFIID component TAF7 functionally interacts with both TFIIH and P-TEFb
stated in qid: Q24317617
retrieved: 2019-04-08

wikidata id: Q2480972
domain: protein
level: standard
html url: https://4ort.xyz/entity/tata-box-binding-protein-q2480972
markdown url: https://4ort.xyz/entity/tata-box-binding-protein-q2480972.md
facts url summary: https://4ort.xyz/entity/tata-box-binding-protein-q2480972/facts.json
facts url standard: https://4ort.xyz/entity/tata-box-binding-protein-q2480972/facts.json
facts url full: https://4ort.xyz/entity/tata-box-binding-protein-q2480972/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-31T03:28:25.744898Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:20:31.304434+00:00Z