# TAP binding protein

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7684469](https://www.wikidata.org/wiki/Q7684469)  
**Source**: https://4ort.xyz/entity/tap-binding-protein


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O15533)
3. Q20641742
4. [Chaperones and folding of MHC class I molecules in the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
5. [Interactions formed by individually expressed TAP1 and TAP2 polypeptide subunits](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
6. [Cloning and functional characterization of a subunit of the transporter associated with antigen processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
7. [The varicellovirus UL49.5 protein blocks the transporter associated with antigen processing (TAP) by inhibiting essential conformational transitions in the 6+6 transmembrane TAP core complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
8. [The binding of TAPBPR and Tapasin to MHC class I is mutually exclusive](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
9. [Specific targeting of the EBV lytic phase protein BNLF2a to the transporter associated with antigen processing results in impairment of HLA class I-restricted antigen presentation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
10. [Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
11. [Varicelloviruses avoid T cell recognition by UL49.5-mediated inactivation of the transporter associated with antigen processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
12. [Tapasin interacts with the membrane-spanning domains of both TAP subunits and enhances the structural stability of TAP1 x TAP2 Complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
13. [TAPBPR alters MHC class I peptide presentation by functioning as a peptide exchange catalyst](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
14. [Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
15. [Molecular architecture of the TAP-associated MHC class I peptide-loading complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
16. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
17. [Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
18. [Molecular architecture of the TAP-associated MHC class I peptide-loading complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15533&geneProductId=UniProtKB:O15533)
19. [Chaperones and folding of MHC class I molecules in the endoplasmic reticulum](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15533&geneProductId=UniProtKB:O15533)
20. [A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
21. [Distinct functions for the glycans of tapasin and heavy chains in the assembly of MHC class I molecules.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
22. [A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes](http://www.ebi.ac.uk/QuickGO/annotations?protein=O15533&geneProductId=UniProtKB:O15533)
23. [An essential function of tapasin in quality control of HLA-G molecules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O15533)
24. Ensembl Release 99
25. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)
26. Transporter Classification database