# Tachykinin receptor 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561067](https://www.wikidata.org/wiki/Q28561067)  
**Source**: https://4ort.xyz/entity/tachykinin-receptor-1-q28561067


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P14600)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
6. [The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
7. [Exercise reduces GABA synaptic input onto nucleus tractus solitarii baroreceptor second-order neurons via NK1 receptor internalization in spontaneously hypertensive rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
8. [Localization of NK1 receptors and roles of substance-P in subepithelial fibroblasts of rat intestinal villi](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
9. [Neurokinin-1 receptors in cholinergic neurons of the rat ventral pallidum have a predominantly dendritic distribution that is affected by apomorphine when combined with startle-evoking auditory stimulation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
10. [The Role of Substance P in the Marginal Division of the Neostriatum in Learning and Memory is Mediated Through the Neurokinin 1 Receptor in Rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
11. [The effect of neurokinin1 receptor blockade on territorial aggression and in a model of violent aggression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
12. [Central and peripheral expression of neurokinin-1 and neurokinin-3 receptor and substance P-encoding messenger RNAs: peripheral regulation during formalin-induced inflammation and lack of neurokinin receptor expression in primary afferent sensory ne](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
13. [Role of kinins and sensory neurons in the rat pleural leukocyte migration induced by Phoneutria nigriventer spider venom](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
14. [Further Evidence that Central Tachykinin NK-1 Receptors Mediate the Inhibitory Effect of Tachykinins on Angiotensin-Induced Drinking in Rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
15. [Substance P regulates migration in rat intestinal epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
16. [The effect of substance P on asthmatic rat airway smooth muscle cell proliferation, migration, and cytoplasmic calcium concentration in vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
17. [Synaptic plasticity in spinal lamina I projection neurons that mediate hyperalgesia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
18. [Effects of substance P microinjections into the globus pallidus and central nucleus of amygdala on passive avoidance learning in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
19. [Hemodynamic effects of substance P and its receptor antagonist RP67580 in anesthetized rats with carbon tetrachloride-induced cirrhosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
20. [Neurokinin-1 receptor enhances TRPV1 activity in primary sensory neurons via PKCepsilon: a novel pathway for heat hyperalgesia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
21. [Effect of melatonin on the vasopressin secretion as influenced by tachykinin NK-1 receptor agonist and antagonist: in vivo and in vitro studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
22. [Activation of neurokinin-1 receptors during ozone inhalation contributes to epithelial injury and repair](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
23. [NK-1 receptors in the rostral ventromedial medulla contribute to hyperalgesia produced by intraplantar injection of capsaicin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
24. [Tachykinin regulation of cholinergic transmission in the limbic/prefrontal territory of the rat dorsal striatum: implication of new neurokinine 1-sensitive receptor binding site and interaction with enkephalin/mu opioid receptor transmission](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
25. [Tachykinin receptor and neutral endopeptidase gene expression in the rat uterus: characterization and regulation in response to ovarian steroid treatment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
26. [Elimination of rat spinal substance P receptor bearing neurons dissociates cardiovascular and nocifensive responses to nicotinic agonists](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
27. [Intrathecal administration of neurokinin 1 and neurokinin 2 receptor antagonists undermines the savings effect in spinal rats seen in an instrumental learning paradigm](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
28. [Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
29. [Role of the neurokinin-1 receptors in ejaculation in anesthetized rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
30. [Differential effects of dexamethasone, ondansetron and a tachykinin NK1 receptor antagonist (GR205171) on cisplatin-induced changes in behaviour, food intake, pica and gastric function in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
31. [Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
32. [Decreased substance P and NK1 receptor immunoreactivity and function in the spinal cord dorsal horn of morphine-treated neonatal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
33. [Ablation of primary afferent neurons by neonatal capsaicin treatment reduces the susceptibility of the portal hypertensive gastric mucosa to ethanol-induced injury in cirrhotic rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
34. [Physiological and morphological properties of, and effect of substance P on, neurons in the A7 catecholamine cell group in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
35. [TRPV1-mediated protection against endotoxin-induced hypotension and mortality in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
36. [Substance P stimulates late-stage rat osteoblastic bone formation through neurokinin-1 receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
37. [Colorectal distension enforce acute urinary bladder distension-induced hepatic vasoconstriction in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
38. [Direct evidence for the interaction of neurokinin A with the tachykinin NK(1) receptor in tissue](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
39. [Role of tachykinin receptors and melatonin in oxitocin secretion from isolated rat hypothalmo-neurohypophysial system](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
40. [Thiorphan-induced survival and proliferation of rat thymocytes by activation of Akt/survivin pathway and inhibition of caspase-3 activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
41. [Altered neuropeptide Y and neurokinin messenger RNA expression and receptor binding in stress-sensitised rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
42. [Sprouting of substance P-expressing primary afferent central terminals and spinal micturition reflex NK1 receptor dependence after spinal cord injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
43. [Estrogen-dependent regulation of neurokinin 3 receptor-mediated uterine contractility in the rat](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P14600)
44. ensembl Release 106