# Synuclein alpha

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28560432](https://www.wikidata.org/wiki/Q28560432)  
**Source**: https://4ort.xyz/entity/synuclein-alpha-q28560432


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P37377)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
5. [Rat alpha-synuclein interacts with Tat binding protein 1, a component of the 26S proteasomal complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
6. [Desipramine modulation of alpha-, gamma-synuclein, and the norepinephrine transporter in an animal model of depression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
7. [Identification of novel proteins associated with both alpha-synuclein and DJ-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
8. [p25alpha Stimulates alpha-synuclein aggregation and is co-localized with aggregated alpha-synuclein in alpha-synucleinopathies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
9. [Membrane-bound α-Synuclein Has a High Aggregation Propensity and the Ability to Seed the Aggregation of the Cytosolic Form](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
10. [Tubulin Seeds α-Synuclein Fibril Formation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
11. [A role for alpha-synuclein in the regulation of dopamine biosynthesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
12. [Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
13. [alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
14. [Parkin cleaves intracellular alpha-synuclein inclusions via the activation of calpain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
15. [Immunolocalization of alpha-synuclein in the rat spinal cord by two novel monoclonal antibodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
16. [Alpha-synuclein immunoreactivity in normal and neoplastic Schwann cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
17. [alpha-Synuclein is differentially expressed in mitochondria from different rat brain regions and dose-dependently down-regulates complex I activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
18. [Alpha-synuclein protects cerebellar granule neurons against 6-hydroxydopamine-induced death](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
19. [Alpha-synuclein in the nucleus accumbens induces changes in cocaine behaviour in rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
20. [Localization of alpha-, beta-, and gamma-synuclein during neuronal development and alterations associated with the neuronal response to axonal trauma](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
21. [Extensive nuclear localization of alpha-synuclein in normal rat brain neurons revealed by a novel monoclonal antibody](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
22. [Alpha-synuclein-positive structures induced in leupeptin-infused rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
23. [Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
24. [Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
25. [Differential localization of alpha-, beta- and gamma-synucleins in the rat CNS](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
26. [Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
27. [Expression of alpha-synuclein in different brain parts of adult and aged rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
28. [Distribution of α‐ and γ‐synucleins in the adult rat brain and their modification by high‐dose cocaine treatment](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
29. [Regulation of alpha-synuclein by bFGF in cultured ventral midbrain dopaminergic neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
30. [Mutant LRRK2 Toxicity in Neurons Depends on LRRK2 Levels and Synuclein But Not Kinase Activity or Inclusion Bodies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
31. [Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
32. [Desipramine induced changes in the norepinephrine transporter, alpha- and gamma-synuclein in the hippocampus, amygdala and striatum](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P37377)
33. ensembl Release 104