# Synthesis of cytochrome C oxidase 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135429](https://www.wikidata.org/wiki/Q21135429)  
**Source**: https://4ort.xyz/entity/synthesis-of-cytochrome-c-oxidase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/O75880)
3. Q20641742
4. [The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
5. [Human mitochondrial cytochrome c oxidase assembly factor COX18 acts transiently as a membrane insertase within the subunit 2 maturation module](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
6. [Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
7. [COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
8. [COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
9. [Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
10. [An AP-MS- and BioID-compatible MAC-tag enables comprehensive mapping of protein interactions and subcellular localizations](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
12. [Unexpected vascular enrichment of SCO1 over SCO2 in mammalian tissues: implications for human mitochondrial disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
13. [Mutations in COA6 cause cytochrome c oxidase deficiency and neonatal hypertrophic cardiomyopathy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
14. [Identification and characterization of human cDNAs specific to BCS1, PET112, SCO1, COX15, and COX11, five genes involved in the formation and function of the mitochondrial respiratory chain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
15. [Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
16. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O75880)
17. Ensembl Release 99