# Syntaxin 4

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21106672](https://www.wikidata.org/wiki/Q21106672)  
**Source**: https://4ort.xyz/entity/syntaxin-4


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q12846)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
5. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
6. [Protease-activated receptor-1 activation of endothelial cells induces protein kinase Calpha-dependent phosphorylation of syntaxin 4 and Munc18c: role in signaling p-selectin expression](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
7. [Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
8. [A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
9. [Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
10. [A proteome-scale map of the human interactome network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
11. [Sec22b regulates phagosomal maturation and antigen crosspresentation by dendritic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
12. [Widespread macromolecular interaction perturbations in human genetic disorders](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
13. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
14. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
15. [Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
16. [The syntaxin family of vesicular transport receptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
18. [Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
19. [Syntaxin 4 is required for acid sphingomyelinase activity and apoptotic function](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
20. [Syntaxin-4 defines a domain for activity-dependent exocytosis in dendritic spines](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
21. [Syntaxin-4 is essential for IgE secretion by plasma cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
22. [Syntaxins 3 and 4 are concentrated in separate clusters on the plasma membrane before the establishment of cell polarity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
23. [Involvement of Munc18 isoforms in the regulation of granule exocytosis in neutrophils](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
24. [Proteomic analysis of podocyte exosome-enriched fraction from normal human urine](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
25. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
26. [Syntaxins 3 and 4 mediate vesicular trafficking of α5β1 and α3β1 integrins and cancer cell migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
27. [Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
28. [The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12846&geneProductId=UniProtKB:Q12846)
29. [The impact of extracellular syntaxin4 on HaCaT keratinocyte behavior](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
30. [The dysbindin-containing complex (BLOC-1) in brain: developmental regulation, interaction with SNARE proteins and role in neurite outgrowth](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
31. [MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
32. [The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
33. [Involvement of syntaxin 4 in the transport of membrane-type 1 matrix metalloproteinase to the plasma membrane in human gastric epithelial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
34. [Syntaxin 4 Up-Regulation Increases Efficiency of Insulin Release in Pancreatic Islets From Humans With and Without Type 2 Diabetes Mellitus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12846)
35. Ensembl Release 99
36. Transporter Classification database