# Synaptotagmin I

> mammalian protein found in Mus musculus

**Wikidata**: [Q21990096](https://www.wikidata.org/wiki/Q21990096)  
**Source**: https://4ort.xyz/entity/synaptotagmin-i


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P46096)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
5. [Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
6. [PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
7. [SV2B regulates synaptotagmin 1 by direct interaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
8. [Functional dissection of the interactions of stonin 2 with the adaptor complex AP-2 and synaptotagmin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
9. [Identification of neuroglobin-interacting proteins using yeast two-hybrid screening](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
10. [WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
11. [Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
12. [Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
14. [Synaptotagmin IV regulates glial glutamate release](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
15. [Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
16. [Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
17. [Conformational switch of syntaxin-1 controls synaptic vesicle fusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
18. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
19. [Synaptotagmin VI and VIII and syntaxin 2 are essential for the mouse sperm acrosome reaction](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
20. [Synaptotagmin IV regulates glial glutamate release](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
21. [Molecular cloning, expression, and characterization of a novel class of synaptotagmin (Syt XIV) conserved from Drosophila to humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
22. [Phospholipid composition dependence of Ca2+-dependent phospholipid binding to the C2A domain of synaptotagmin IV](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
23. [Doc2 supports spontaneous synaptic transmission by a Ca(2+)-independent mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
24. [Scrg1, a novel protein of the CNS is targeted to the large dense‐core vesicles in neuronal cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
25. [LRRK2 controls synaptic vesicle storage and mobilization within the recycling pool](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
26. [Somatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channels](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
27. [Synaptotagmin IV regulates dense core vesicle (DCV) release in LbetaT2 cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
28. [SV2B regulates synaptotagmin 1 by direct interaction](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
29. [Distinct developmental expression of synaptotagmin I and IX in the mouse brain](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
30. [Loss of alpha-tubulin polyglutamylation in ROSA22 mice is associated with abnormal targeting of KIF1A and modulated synaptic function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
31. [Calmodulin and lipid binding to synaptobrevin regulates calcium-dependent exocytosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
32. [Molecular determinants of synapsin targeting to presynaptic terminals](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
33. [Somatodendritic dopamine release requires synaptotagmin 4 and 7 and the participation of voltage-gated calcium channels](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
34. [Molecular determinants of synapsin targeting to presynaptic terminals](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
35. [Synaptotagmin IV regulates dense core vesicle (DCV) release in LbetaT2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
36. [Synaptotagmin I: a major Ca2+ sensor for transmitter release at a central synapse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
37. [SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
38. [The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
39. [Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
40. [Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
41. [SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
42. [Intracellular calcium dependence of large dense-core vesicle exocytosis in the absence of synaptotagmin I](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
43. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P46096&geneProductId=UniProtKB:P46096)
44. [Synaptotagmin I functions as a calcium regulator of release probability](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P46096)
45. ensembl Release 106
46. Transporter Classification database