# Synaptotagmin 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21171815](https://www.wikidata.org/wiki/Q21171815)  
**Source**: https://4ort.xyz/entity/synaptotagmin-1-q21171815


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P21579)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21579&geneProductId=UniProtKB:P21579)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
7. [Direct interaction of the Rab3 effector RIM with Ca2+ channels, SNAP-25, and synaptotagmin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
8. [Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
9. [Human SCAMP5, a novel secretory carrier membrane protein, facilitates calcium-triggered cytokine secretion by interaction with SNARE machinery](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
10. [S100A13-C2A binary complex structure-a key component in the acidic fibroblast growth factor for the non-classical pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
11. [Systematic protein-protein interaction mapping for clinically relevant human GPCRs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
12. [Expanding the substantial interactome of NEMO using protein microarrays](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
13. [Alternative splicing of the voltage-gated Ca2+ channel beta4 subunit creates a uniquely folded N-terminal protein binding domain with cell-specific expression in the cerebellar cortex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
14. [Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21579&geneProductId=UniProtKB:P21579)
15. [Sr2+ binding to the Ca2+ binding site of the synaptotagmin 1 C2B domain triggers fast exocytosis without stimulating SNARE interactions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
16. [Intracellular distribution of differentially phosphorylated dual‐specificity tyrosine phosphorylation‐regulated kinase 1A (DYRK1A)](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
17. [Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
18. [SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P21579)
19. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P21579&geneProductId=UniProtKB:P21579)
20. Ensembl Release 99
21. UMLS 2023
22. Transporter Classification database