# SUZ12 polycomb repressive complex 2 subunit

> mammalian protein found in Mus musculus

**Wikidata**: [Q21431161](https://www.wikidata.org/wiki/Q21431161)  
**Source**: https://4ort.xyz/entity/suz12-polycomb-repressive-complex-2-subunit-q21431161


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q80U70)
3. Q20641742
4. [STAT6-mediated displacement of polycomb by trithorax complex establishes long-term maintenance of GATA3 expression in T helper type 2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
5. [Terminal epidermal differentiation is regulated by the interaction of Fra-2/AP-1 with Ezh2 and ERK1/2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
6. [Distinct roles of Polycomb group gene products in transcriptionally repressed and active domains of Hoxb8](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
8. [Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
9. [Combined Overexpression of JARID2, PRDM14, ESRRB, and SALL4A Dramatically Improves Efficiency and Kinetics of Reprogramming to Induced Pluripotent Stem Cells.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
10. [Jarid2 regulates mouse epidermal stem cell activation and differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
11. [Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
12. [The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
13. [BRCA1 is a negative modulator of the PRC2 complex](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
14. [JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
15. [Reverse engineering a mouse embryonic stem cell-specific transcriptional network reveals a new modulator of neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
16. [Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
17. [Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
18. [Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
19. [The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
21. [Tsix RNA and the germline factor, PRDM14, link X reactivation and stem cell reprogramming](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
22. [Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
23. [Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A to heritable gene silencing and X inactivation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
24. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
25. [Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
26. [Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
27. [Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
28. [Jarid2/Jumonji coordinates control of PRC2 enzymatic activity and target gene occupancy in pluripotent cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
29. [Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
30. [Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q80U70&geneProductId=UniProtKB:Q80U70)
31. [Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
32. [Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
33. [Polycomb PHF19 binds H3K36me3 and recruits PRC2 and demethylase NO66 to embryonic stem cell genes during differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
34. [Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
35. [Suz12 is essential for mouse development and for EZH2 histone methyltransferase activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
36. [Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q80U70)
37. ensembl Release 106