# Suppressor of fused Dmel_CG6054

> protein found in Drosophila melanogaster

**Wikidata**: [Q29821023](https://www.wikidata.org/wiki/Q29821023)  
**Source**: https://4ort.xyz/entity/suppressor-of-fused-dmel-cg6054


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9VG38)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VG38&geneProductId=UniProtKB:Q9VG38)
5. [The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
6. [A protein interaction map of Drosophila melanogaster](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
7. [Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
8. [Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
9. [Suppressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VG38&geneProductId=UniProtKB:Q9VG38)
10. [Suppressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
11. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
13. [The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VG38&geneProductId=UniProtKB:Q9VG38)
14. [Identification of a tetrameric hedgehog signaling complex](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VG38&geneProductId=UniProtKB:Q9VG38)
15. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VG38&geneProductId=UniProtKB:Q9VG38)
16. [The Kinesin-related protein Costal2 associates with membranes in a Hedgehog-sensitive, Smoothened-independent manner](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
17. [Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
18. [Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9VG38&geneProductId=UniProtKB:Q9VG38)
19. [Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
20. [Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
21. [The Hedgehog-induced Smoothened conformational switch assembles a signaling complex that activates Fused by promoting its dimerization and phosphorylation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
22. [Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
23. [Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
24. [The fused protein kinase regulates Hedgehog-stimulated transcriptional activation in Drosophila Schneider 2 cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9VG38)
25. ensembl Release 106