# Superoxide dismutase 1, soluble

> mammalian protein found in Mus musculus

**Wikidata**: [Q15328173](https://www.wikidata.org/wiki/Q15328173)  
**Source**: https://4ort.xyz/entity/superoxide-dismutase-1-soluble


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P08228)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
5. [In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
6. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
7. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
8. [The nature of antioxidant defense mechanisms: a lesson from transgenic studies](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
9. [Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
10. [Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
11. [Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
12. [Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
13. [Cellular response of antioxidant metalloproteins in Cu/Zn SOD transgenic mice exposed to hyperoxia](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
14. [Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
15. [Reduced Fertility in Female Mice Lacking Copper-Zinc Superoxide Dismutase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
16. [Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
17. [Targeted deletion of the cytosolic Cu/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
18. [Copper, zinc-superoxide dismutase protein but not mRNA is lower in copper-deficient mice and mice lacking the copper chaperone for superoxide dismutase](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
19. [Complex III releases superoxide to both sides of the inner mitochondrial membrane](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
20. [Developmental changes in murine brain antioxidant enzymes](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
21. [Assignment of the gene for cytoplasmic glutamate-oxaloacetate transaminase to mouse chromosome 19 using chinese hamster x mouse somatic cell hybrids](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
22. [Assignment of the gene for cytoplasmic superoxide dismutase ( Sod-1 ) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
23. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
24. [Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
25. [SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
26. [A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
27. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
28. [In vitro photochemical cataract in mice lacking copper-zinc superoxide dismutase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
29. [Copper/zinc superoxide dismutase attenuates neuronal cell death by preventing extracellular signal-regulated kinase activation after transient focal cerebral ischemia in mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
30. [Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
31. [Targeted deletion of the cytosolic Cu/Zn-superoxide dismutase gene (Sod1) increases susceptibility to noise-induced hearing loss](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
32. [Increased superoxide and vascular dysfunction in CuZnSOD-deficient mice](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
33. [Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
34. [The nature of antioxidant defense mechanisms: a lesson from transgenic studies](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
35. [Pivotal role of Cu,Zn-superoxide dismutase in endothelium-dependent hyperpolarization](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
36. [Targeted disruption of the mouse Sod I gene makes the hearts vulnerable to ischemic reperfusion injury](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
37. [Cellular response of antioxidant metalloproteins in Cu/Zn SOD transgenic mice exposed to hyperoxia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
38. [Reduced Fertility in Female Mice Lacking Copper-Zinc Superoxide Dismutase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
39. [Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
40. [Assignment of the gene for cytoplasmic superoxide dismutase ( Sod-1 ) to a region of chromosome 16 and of Hprt to a region of the X chromosome in the mouse](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
41. [Complex III releases superoxide to both sides of the inner mitochondrial membrane](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
42. [Copper, zinc-superoxide dismutase protein but not mRNA is lower in copper-deficient mice and mice lacking the copper chaperone for superoxide dismutase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
43. [Assignment of the gene for cytoplasmic glutamate-oxaloacetate transaminase to mouse chromosome 19 using chinese hamster x mouse somatic cell hybrids](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
44. [Developmental changes in murine brain antioxidant enzymes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
45. [Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P08228)
46. [Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
47. [A mitochondrial protein compendium elucidates complex I disease biology](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
48. [Proteolipid protein is required for transport of sirtuin 2 into CNS myelin](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
49. [Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)
50. [Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c](http://www.ebi.ac.uk/QuickGO/annotations?protein=P08228&geneProductId=UniProtKB:P08228)