# Structural maintenance of chromosomes flexible hinge domain containing 1

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21135635](https://www.wikidata.org/wiki/Q21135635)  
**Source**: https://4ort.xyz/entity/structural-maintenance-of-chromosomes-flexible-hinge-domain-containing-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/A6NHR9)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9)
5. [Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=A6NHR9&geneProductId=UniProtKB:A6NHR9)
7. [Structural Maintenance of Chromosomes Flexible Hinge Domain Containing 1 (SMCHD1) Promotes Non-homologous End Joining and Inhibits Homologous Recombination Repair upon DNA Damage](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9)
8. [SMCHD1 accumulates at DNA damage sites and facilitates the repair of DNA double-strand breaks](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9)
9. [SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9)
10. [De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:A6NHR9)
11. Ensembl Release 99