# Spi-1 proto-oncogene

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21108730](https://www.wikidata.org/wiki/Q21108730)  
**Source**: https://4ort.xyz/entity/spi-1-proto-oncogene


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P17947)
3. Q20641742
4. [Swiss-Prot](http://www.uniprot.org/uniprot/P17433.txt?version=154)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17947&geneProductId=UniProtKB:P17947)
7. [A Novel In-Frame Deletion in the Leucine Zipper Domain of C/EBPε Leads to Neutrophil-Specific Granule Deficiency](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
8. [Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
9. [Gain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
10. [Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
11. [PML/RARalpha targets promoter regions containing PU.1 consensus and RARE half sites in acute promyelocytic leukemia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
12. [Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
13. [The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
14. [The hematopoietic transcription factor PU.1 represses gelatinase A transcription in glomerular mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
15. [CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
16. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17947&geneProductId=UniProtKB:P17947)
17. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17947&geneProductId=UniProtKB:P17947)
18. [Metallothionein-1 isoforms and vimentin are direct PU.1 downstream target genes in leukemia cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
19. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
20. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
21. [Hepatitis C Virus-Induced Changes in MicroRNA 107 (miRNA-107) and miRNA-449a Modulate CCL2 by Targeting the Interleukin-6 Receptor Complex in Hepatitis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
22. [Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?protein=P17947&geneProductId=UniProtKB:P17947)
23. [Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17947)
24. Ensembl Release 99
25. [Identifiers.org](https://registry.identifiers.org/registry/uniprot)