# Sphingosine kinase 1

> mammalian protein found in Mus musculus

**Wikidata**: [Q14913839](https://www.wikidata.org/wiki/Q14913839)  
**Source**: https://4ort.xyz/entity/sphingosine-kinase-1


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8CI15)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8CI15&geneProductId=UniProtKB:Q8CI15)
6. [The nucleotide-binding site of human sphingosine kinase 1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
7. [Molecular Cloning and Functional Characterization of Murine Sphingosine Kinase](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
8. [The Sphingosine 1-Phosphate Transporter, SPNS2, Functions as a Transporter of the Phosphorylated Form of the Immunomodulating Agent FTY720](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
9. [Pathological roles of the VEGF/SphK pathway in Niemann–Pick type C neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
10. [Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
11. [Sphingosine Kinase 1 Cooperates with Autophagy to Maintain Endocytic Membrane Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
12. [SphK1 and SphK2, sphingosine kinase isoenzymes with opposing functions in sphingolipid metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
13. [Coupling between endocytosis and sphingosine kinase 1 recruitment.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
14. [Essential role for sphingosine kinases in neural and vascular development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
15. [Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
16. [A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
17. [Sphingosine and Sphingosine Kinase 1 Involvement in Endocytic Membrane Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8CI15)
18. ensembl Release 106