# Sphingosine kinase 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28559094](https://www.wikidata.org/wiki/Q28559094)  
**Source**: https://4ort.xyz/entity/sphingosine-kinase-1-q28559094


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q91V26)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
5. [FHL2/SLIM3 Decreases Cardiomyocyte Survival by Inhibitory Interaction With Sphingosine Kinase-1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
6. [Extracellular release of newly synthesized sphingosine‐1‐phosphate by cerebellar granule cells and astrocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
7. [Neurotrophic signalling pathway triggered by prosaposin in PC12 cells occurs through lipid rafts](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
8. [Sphingosine-1-Phosphate Is a Key Regulator of Proliferation and Differentiation in Retina Photoreceptors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
9. [Involvement of Sphingosine-1-Phosphate in Glutamate Secretion in Hippocampal Neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
10. [Novel role of sphingosine kinase 1 as a mediator of neurotrophin‐3 action in oligodendrocyte progenitors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
11. [Signaling Pathways Involved in Sphingosine Kinase Activation and Sphingosine-1-Phosphate Release in Rat Myometrium in Late Pregnancy: Role in the Induction of Cyclooxygenase 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
12. [Endothelin-1 Inhibits Apoptosis through a Sphingosine Kinase 1-Dependent Mechanism in Uterine Leiomyoma ELT3 Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
13. [Differential transactivation of sphingosine-1-phosphate receptors modulates NGF-induced neurite extension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
14. [Progesterone-induced sphingosine kinase-1 expression in the rat uterus during pregnancy and signaling consequences](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
15. [Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase‐1 expression and activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
16. [Cloning and characterization of rat sphingosine kinase 1 with an N-terminal extension](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
17. [Oxidative Stress–Dependent Sphingosine Kinase-1 Inhibition Mediates Monoamine Oxidase A–Associated Cardiac Cell Apoptosis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
18. [Sphingosine Kinase Activity and Sphingosine-1 Phosphate Production in Rat Pancreatic Islets and INS-1 Cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
19. [Transcription factor specificity protein 1 (Sp1) is the main regulator of nerve growth factor‐induced sphingosine kinase 1 gene expression of the rat pheochromocytoma cell line, PC12](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
20. [Sphk1 mediates neuroinflammation and neuronal injury via TRAF2/NF-κB pathways in activated microglia in cerebral ischemia reperfusion](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q91V26)
21. ensembl Release 106