# Sphingosine-1-phosphate receptor 1

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28562394](https://www.wikidata.org/wiki/Q28562394)  
**Source**: https://4ort.xyz/entity/sphingosine-1-phosphate-receptor-1-q28562394


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/P48303)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
5. [EDG1 receptor stimulation leads to cardiac hypertrophy in rat neonatal myocytes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
6. [Cloning of the rat edg-1 immediate-early gene: expression pattern suggests diverse functions](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
7. [Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
8. [EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
9. [Blood lipid mediator sphingosine 1-phosphate potently stimulates platelet-derived growth factor-A and -B chain expression through S1P1-Gi-Ras-MAPK-dependent induction of Kruppel-like factor 5](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
10. [Inhibitory regulation of Rac activation, membrane ruffling, and cell migration by the G protein-coupled sphingosine-1-phosphate receptor EDG5 but not EDG1 or EDG3](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P48303)
11. ensembl Release 106