# SPG7 matrix AAA peptidase subunit, paraplegin

> mammalian protein found in Homo sapiens

**Wikidata**: [Q7135735](https://www.wikidata.org/wiki/Q7135735)  
**Source**: https://4ort.xyz/entity/spg7-matrix-aaa-peptidase-subunit-paraplegin


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q9UQ90)
3. Q20641742
4. [Spastic Paraplegia and OXPHOS Impairment Caused by Mutations in Paraplegin, a Nuclear-Encoded Mitochondrial Metalloprotease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
6. [Molecular and Functional Analyses of the Human and Mouse Genes Encoding AFG3L1, a Mitochondrial Metalloprotease Homologous to the Human Spastic Paraplegia Protein](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
7. [Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
8. [SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
9. [A Proteome-Scale Map of the Human Interactome Network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
10. [Next-generation sequencing to generate interactome datasets](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
11. [Towards a proteome-scale map of the human protein–protein interaction network](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
12. [Spastic Paraplegia and OXPHOS Impairment Caused by Mutations in Paraplegin, a Nuclear-Encoded Mitochondrial Metalloprotease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ90&geneProductId=UniProtKB:Q9UQ90)
13. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ90&geneProductId=UniProtKB:Q9UQ90)
14. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UQ90)
15. [SPG7 Is an Essential and Conserved Component of the Mitochondrial Permeability Transition Pore](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UQ90&geneProductId=UniProtKB:Q9UQ90)
16. Ensembl Release 99