Spectrin beta, erythrocytic
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P279
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P11277
additional property: PropertyValue
  property ID: P361
  value: CH domain superfamily
additional property: PropertyValue
  property ID: P361
  value: Spectrin, beta subunit
additional property: PropertyValue
  property ID: P361
  value: Calponin homology domain, protein family
additional property: PropertyValue
  property ID: P527
  value: Spectrin/alpha-actinin
additional property: PropertyValue
  property ID: P527
  value: Spectrin repeat
additional property: PropertyValue
  property ID: P527
  value: Actinin-type actin-binding domain, conserved site
additional property: PropertyValue
  property ID: P637
  value: NP_001020029
additional property: PropertyValue
  property ID: P637
  value: XP_011535407
additional property: PropertyValue
  property ID: P637
  value: XP_016877101
additional property: PropertyValue
  property ID: P638
  value: 1S35
additional property: PropertyValue
  property ID: P638
  value: 3EDU
additional property: PropertyValue
  property ID: P638
  value: 3F57
additional property: PropertyValue
  property ID: P680
  value: actin filament binding
additional property: PropertyValue
  property ID: P680
  value: structural constituent of cytoskeleton
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P681
  value: spectrin
additional property: PropertyValue
  property ID: P681
  value: intrinsic component of the cytoplasmic side of the plasma membrane
additional property: PropertyValue
  property ID: P681
  value: cell surface
additional property: PropertyValue
  property ID: P682
  value: MAPK cascade
additional property: PropertyValue
  property ID: P682
  value: axon guidance
additional property: PropertyValue
  property ID: P682
  value: endoplasmic reticulum to Golgi vesicle-mediated transport
additional property: PropertyValue
  property ID: P702
  value: SPTB
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000374370
additional property: PropertyValue
  property ID: P705
  value: ENSP00000374372
additional property: PropertyValue
  property ID: P705
  value: ENSP00000451324
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 16
      unique citations norm: 0.006
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 16
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P279:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P11277
    source count: 1
    confidence: 0.2
  P361:
    value: Q41797968
    source count: 1
    confidence: 0.2
    value label: CH domain superfamily
  P361:
    value: Q24768109
    source count: 1
    confidence: 0.2
    value label: Spectrin, beta subunit
  P361:
    value: Q83134492
    source count: 1
    confidence: 0.2
    value label: Calponin homology domain, protein family
  P361:
    value: Q95351524
    source count: 1
    confidence: 0.2
    value label: Actinin-type actin-binding domain, conserved site, protein family
  P361:
    value: Q95351962
    source count: 1
    confidence: 0.2
    value label: Spectrin repeat, protein family
  P527:
    value: Q24740273
    source count: 1
    confidence: 0.2
    value label: Spectrin/alpha-actinin
  P527:
    value: Q24778004
    source count: 1
    confidence: 0.2
    value label: Spectrin repeat
  P527:
    value: Q24745383
    source count: 1
    confidence: 0.2
    value label: Actinin-type actin-binding domain, conserved site
  P527:
    value: Q24723587
    source count: 1
    confidence: 0.2
    value label: Calponin homology domain
  P637:
    value: NP_001020029
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011535407
    source count: 1
    confidence: 0.2
  P637:
    value: XP_016877101
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001342365
    source count: 1
    confidence: 0.2
  P637:
    value: NP_001342366
    source count: 1
    confidence: 0.2
  P638:
    value: 1S35
    source count: 1
    confidence: 0.2
  P638:
    value: 3EDU
    source count: 1
    confidence: 0.2
  P638:
    value: 3F57
    source count: 1
    confidence: 0.2
  P638:
    value: 3KBT
    source count: 1
    confidence: 0.2

value: 3KBU
source count: 1
confidence: 0.2

value: Q14860806
source count: 1
confidence: 0.2
value label: actin filament binding

value: Q14864144
source count: 1
confidence: 0.2
value label: structural constituent of cytoskeleton

value: Q167149
source count: 5
confidence: 1.0
value label: protein binding

value: Q14877657
source count: 1
confidence: 0.2
value label: ankyrin binding

value: Q14863962
source count: 3
confidence: 0.6
value label: actin binding

value: Q420870
source count: 2
confidence: 0.4
value label: spectrin

value: Q14906006
source count: 1
confidence: 0.2
value label: intrinsic component of the cytoplasmic side of the plasma membrane

value: Q189094
source count: 1
confidence: 0.2
value label: cell surface

value: Q5058180
source count: 1
confidence: 0.2
value label: cell cortex

value: Q14860845
source count: 1
confidence: 0.2
value label: actin cytoskeleton

value: Q14758900
source count: 1
confidence: 0.2
value label: MAPK cascade

value: Q2034716
source count: 1
confidence: 0.2
value label: axon guidance

value: Q14882482
source count: 1
confidence: 0.2
value label: endoplasmic reticulum to Golgi vesicle-mediated transport

value: Q21095296
source count: 1
confidence: 0.2
value label: actin filament capping

value: Q14864151
source count: 1
confidence: 0.2
value label: cytoskeleton organization

value: Q18031692
source count: 1
confidence: 0.2
value label: SPTB

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000374370
source count: 1
confidence: 0.2

value: ENSP00000374372
source count: 1
confidence: 0.2

value: ENSP00000451324
source count: 1
confidence: 0.2

value: ENSP00000495909
source count: 1
confidence: 0.2

source: Identification and functional characterization of protein 4.1R and actin-binding sites in erythrocyte beta spectrin: regulation of the interactions by phosphatidylinositol-4,5-bisphosphate
stated in qid: Q24311796
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Spectrin alpha II and beta II isoforms interact with high affinity at the tetramerization site
stated in qid: Q24306190
retrieved: 2019-04-08

source: A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome
stated in qid: Q24317313
retrieved: 2019-04-08

source: The muscle regulatory and structural protein MLP is a cytoskeletal binding partner of betaI-spectrin
stated in qid: Q28118047
retrieved: 2019-04-08

source: Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex
stated in qid: Q24301548
retrieved: 2019-04-08

source: Ankyrin binds to two distinct cytoplasmic domains of Na,K-ATPase alpha subunit
stated in qid: Q24310792
retrieved: 2019-04-08

source: Full-length sequence of the cDNA for human erythroid beta-spectrin
stated in qid: Q24338786
retrieved: 2019-04-08

source: Spectrin cagliari. an Ala-->Gly substitution in helix 1 of beta spectrin repeat 17 that severely disrupts the structure and self-association of the erythrocyte spectrin heterodimer
stated in qid: Q28115293
retrieved: 2019-04-08

source: Adducin: structure, function and regulation
stated in qid: Q24290117
retrieved: 2019-04-08

source: Aciculin and its relation to dystrophin: immunocytochemical studies in human normal and Duchenne dystrophy quadriceps muscles
stated in qid: Q22254381
retrieved: 2018-03-27

source: The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes
stated in qid: Q24299885
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21127192
domain: protein
level: standard
html url: https://4ort.xyz/entity/spectrin-beta-erythrocytic
markdown url: https://4ort.xyz/entity/spectrin-beta-erythrocytic.md
facts url summary: https://4ort.xyz/entity/spectrin-beta-erythrocytic/facts.json
facts url standard: https://4ort.xyz/entity/spectrin-beta-erythrocytic/facts.json
facts url full: https://4ort.xyz/entity/spectrin-beta-erythrocytic/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-24T05:48:19.790413Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T15:25:56.647217+00:00Z