# Spastin Dmel_CG5977

> protein found in Drosophila melanogaster

**Wikidata**: [Q29812472](https://www.wikidata.org/wiki/Q29812472)  
**Source**: https://4ort.xyz/entity/spastin-dmel-cg5977


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q8I0P1)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
5. [Drosophila Atlastin regulates the stability of muscle microtubules and is required for synapse development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
6. [Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8I0P1&geneProductId=UniProtKB:Q8I0P1)
7. [Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8I0P1&geneProductId=UniProtKB:Q8I0P1)
8. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8I0P1&geneProductId=UniProtKB:Q8I0P1)
9. [The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8I0P1&geneProductId=UniProtKB:Q8I0P1)
10. [Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
11. [Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
13. [The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
14. [Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
15. [The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
16. [Spastin, atlastin, and ER relocalization are involved in axon but not dendrite regeneration.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
17. [Clasp-mediated microtubule bundling regulates persistent motility and contact repulsion in Drosophila macrophages in vivo.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
18. [The centrosome in human genetic disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
19. [The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function.](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8I0P1&geneProductId=UniProtKB:Q8I0P1)
20. [Spastin binds to lipid droplets and affects lipid metabolism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
21. [Differential regulation of dendritic and axonal development by the novel Krüppel-like factor Dar1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8I0P1)
22. ensembl Release 106