# Sp3 transcription factor

> mammalian protein found in Homo sapiens

**Wikidata**: [Q21107297](https://www.wikidata.org/wiki/Q21107297)  
**Source**: https://4ort.xyz/entity/sp3-transcription-factor


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q02447)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
5. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02447&geneProductId=UniProtKB:Q02447)
6. [Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
7. [The transcriptional repressor Sp3 is associated with CK2-phosphorylated histone deacetylase 2](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
8. [Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
9. [Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
10. [Co-operative interactions between NFAT (nuclear factor of activated T cells) c1 and the zinc finger transcription factors Sp1/Sp3 and Egr-1 regulate MT1-MMP (membrane type 1 matrix metalloproteinase) transcription by glomerular mesangial cells](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
11. [A census of human transcription factors: function, expression and evolution](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
12. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
13. [Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
14. [Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
15. [Sp3 is a transcriptional activator of the human alpha2(I) collagen gene](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
16. [ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
17. [Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02447)
18. ensembl Release 95
19. UMLS 2023