# Sonic hedgehog signaling molecule

> mammalian protein found in Rattus norvegicus

**Wikidata**: [Q28561767](https://www.wikidata.org/wiki/Q28561767)  
**Source**: https://4ort.xyz/entity/sonic-hedgehog-signaling-molecule


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q63673)
3. Q20641742
4. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
5. [Sonic hedgehog ligand partners with caveolin-1 for intracellular transport](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
6. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
7. [Processing-dependent trafficking of Sonic hedgehog to the regulated secretory pathway in neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
8. [Intrinsic facilitation of adult peripheral nerve regeneration by the Sonic hedgehog morphogen](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
9. [High frequency stimulation induces sonic hedgehog release from hippocampal neurons](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
10. [Hypoxia-induced compensatory effect as related to Shh and HIF-1alpha in ischemia embryo rat heart](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
11. [Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
12. [Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
13. [Sonic hedgehog directs specialised mesoderm differentiation in the intestine and pancreas](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
14. [Sonic Hedgehog Promotes Rod Photoreceptor Differentiation in Mammalian Retinal CellsIn Vitro](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
15. [Sonic hedgehog expression in the development of hindgut in ETU-exposed fetal rats](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
16. [Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
17. [Regionalization within the mammalian telencephalon is mediated by changes in responsiveness to Sonic Hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
18. [The conserved barH-like homeobox-2 gene barhl2 acts downstream of orthodentricle-2 and together with iroquois-3 in establishment of the caudal forebrain signaling center induced by Sonic Hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
19. [Sonic hedgehog-patched Gli signaling in the developing rat prostate gland: lobe-specific suppression by neonatal estrogens reduces ductal growth and branching](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
20. [Sonic hedgehog regulates prostatic growth and epithelial differentiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
21. [Retinoic acid is essential for Shh/Hoxd signaling during rat limb outgrowth but not for limb initiation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
22. [Sonic Hedgehog regulates brain-derived neurotrophic factor in normal and regenerating cavernous nerves.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
23. [Pituitary adenylate cyclase-activating polypeptide and sonic hedgehog interact to control cerebellar granule precursor cell proliferation](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
24. [Regulation of cavernous nerve injury-induced apoptosis by sonic hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
25. [Sonic hedgehog exerts distinct, stage-specific effects on tongue and taste papilla development](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
26. [The upregulated expression of sonic hedgehog in motor neurons after rat facial nerve axotomy](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
27. [Sonic hedgehog cascade is required for penile postnatal morphogenesis, differentiation, and adult homeostasis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
28. [Spatial expression of Sonic hedgehog in the lung epithelium during branching morphogenesis](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
29. [Extracellular and intracellular regulation of oligodendrocyte development: roles of Sonic hedgehog and expression of E proteins](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
30. [Sonic hedgehog induces response of commissural axons to Semaphorin repulsion during midline crossing](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
31. [Significance of sonic hedgehog signaling after massive hepatectomy in a rat.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
32. [Erythropoietin and sonic hedgehog mediate the neuroprotective effects of brain-derived neurotrophic factor against mitochondrial inhibition](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
33. [Sonic Hedgehog gene delivery to the rodent heart promotes angiogenesis via iNOS/netrin-1/PKC pathway](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q63673)
34. ensembl Release 106