# Sonic hedgehog signaling molecule

> mammalian protein found in Homo sapiens

**Wikidata**: [Q2477760](https://www.wikidata.org/wiki/Q2477760)  
**Source**: https://4ort.xyz/entity/sonic-hedgehog-signaling-molecule-q2477760


## References

1. UniProt
2. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q15465)
3. Q20641742
4. Freebase Data Dumps. 2013
5. [The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
6. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
7. [The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
8. [Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
9. [A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
10. [The sonic hedgehog-patched-gli pathway in human development and disease](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
11. [Immunohistochemical analysis of Sonic hedgehog signalling in normal human urinary tract development](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
12. [SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
13. [Reduced thymocyte development in sonic hedgehog knockout embryos](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
14. [Mutations in the human Sonic Hedgehog gene cause holoprosencephaly](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
15. [Cerberus is a feedback inhibitor of Nodal asymmetric signaling in the chick embryo](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
16. [Patched1 interacts with cyclin B1 to regulate cell cycle progression](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
17. [Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
18. [Activation of the Hedgehog signaling pathway in T-lineage cells inhibits TCR repertoire selection in the thymus and peripheral T-cell activation](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q15465&geneProductId=UniProtKB:Q15465)
19. Ensembl Release 99