Solute carrier family 7 member 11
type: Thing
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P129
  value: quisqualic acid
additional property: PropertyValue
  property ID: P361
  value: L-type amino acid transporter
additional property: PropertyValue
  property ID: P637
  value: NP_055146
additional property: PropertyValue
  property ID: P637
  value: XP_011530104
additional property: PropertyValue
  property ID: P680
  value: cystine:glutamate antiporter activity
additional property: PropertyValue
  property ID: P680
  value: protein binding
additional property: PropertyValue
  property ID: P680
  value: transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: rough endoplasmic reticulum
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: response to nicotine
additional property: PropertyValue
  property ID: P682
  value: response to oxidative stress
additional property: PropertyValue
  property ID: P682
  value: brain development
additional property: PropertyValue
  property ID: P702
  value: SLC7A11
additional property: PropertyValue
  property ID: P703
  value: Homo sapiens
additional property: PropertyValue
  property ID: P705
  value: ENSP00000280612
additional property: PropertyValue
  property ID: P705
  value: ENSP00000424046
additional property: PropertyValue
  property ID: P7260
  value: 2.A.3.8.18
confidence:
  popularity graph score:
    score: 0.002
    score pct: 0
    tier: established
    components:
      sitelinks: 0
      sitelinks norm: 0.0
      unique citations: 13
      unique citations norm: 0.005
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 0
  unique citations: 13
  monthly pageviews: 0
  yearly pageviews: 0
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P129:
    value: Q756551
    source count: 1
    confidence: 0.2
    value label: quisqualic acid
  P352:
    value: Q9UPY5
    source count: 1
    confidence: 0.2
  P361:
    value: Q24783505
    source count: 2
    confidence: 0.4
    value label: L-type amino acid transporter
  P637:
    value: NP_055146
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011530104
    source count: 1
    confidence: 0.2
  P680:
    value: Q21108356
    source count: 1
    confidence: 0.2
    value label: cystine:glutamate antiporter activity
  P680:
    value: Q167149
    source count: 1
    confidence: 0.2
    value label: protein binding
  P680:
    value: Q14887309
    source count: 1
    confidence: 0.2
    value label: transmembrane transporter activity
  P680:
    value: Q21120740
    source count: 1
    confidence: 0.2
    value label: L-amino acid transmembrane transporter activity
  P681:
    value: Q14327652
    source count: 3
    confidence: 0.6
    value label: integral component of membrane
  P681:
    value: Q7881690
    source count: 1
    confidence: 0.2
    value label: rough endoplasmic reticulum
  P681:
    value: Q14349455
    source count: 3
    confidence: 0.6
    value label: membrane
  P681:
    value: Q14349519
    source count: 1
    confidence: 0.2
    value label: intracellular membrane-bounded organelle
  P681:
    value: Q29548
    source count: 2
    confidence: 0.4
    value label: plasma membrane
  P682:
    value: Q14820664
    source count: 1
    confidence: 0.2
    value label: response to nicotine
  P682:
    value: Q14599315
    source count: 1
    confidence: 0.2
    value label: response to oxidative stress
  P682:
    value: Q14330969
    source count: 1
    confidence: 0.2
    value label: brain development
  P682:
    value: Q14889777
    source count: 1
    confidence: 0.2
    value label: lens fiber cell differentiation
  P682:
    value: Q14913634
    source count: 1
    confidence: 0.2
    value label: platelet aggregation
  P702:
    value: Q18037569
    source count: 1
    confidence: 0.2
    value label: SLC7A11
  P703:
    value: Q15978631
    source count: 1
    confidence: 0.2
    value label: Homo sapiens
  P705:
    value: ENSP00000280612
    source count: 1
    confidence: 0.2
  P705:
    value: ENSP00000424046
    source count: 1
    confidence: 0.2
  P7260:
    value: 2.A.3.8.18
    source count: 2
    confidence: 0.4
citations:
  source: Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
  stated in qid: Q22009401
  retrieved: 2019-04-08

source: CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
stated in qid: Q24296787
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: KSHV attachment and entry are dependent on αVβ3 integrin localized to specific cell surface microdomains and do not correlate with the presence of heparan sulfate
stated in qid: Q24301376
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2018-02-27

source: Differential expression of intestinal membrane transporters in cholera patients
stated in qid: Q24311709
retrieved: 2019-04-08

source: InterPro Release 71.0
stated in qid: Q58943792

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: IUPHAR/BPS Guide to PHARMACOLOGY
stated in qid: Q17091219
retrieved: 2016-08-17

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

source: Transporter Classification database
stated in qid: Q142667
retrieved: 2020-03-13

source: Ensembl Release 99
stated in qid: Q83867711

wikidata id: Q21108357
domain: protein
level: standard
html url: https://4ort.xyz/entity/solute-carrier-family-7-member-11-q21108357
markdown url: https://4ort.xyz/entity/solute-carrier-family-7-member-11-q21108357.md
facts url summary: https://4ort.xyz/entity/solute-carrier-family-7-member-11-q21108357/facts.json
facts url standard: https://4ort.xyz/entity/solute-carrier-family-7-member-11-q21108357/facts.json
facts url full: https://4ort.xyz/entity/solute-carrier-family-7-member-11-q21108357/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-06T13:09:23.015761Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-05-03T14:25:14.046139+00:00Z