# solute carrier family 6 member 3

> mammalian protein found in Homo sapiens

**Wikidata**: [Q2271947](https://www.wikidata.org/wiki/Q2271947)  
**Wikipedia**: [English](https://en.wikipedia.org/wiki/Dopamine_transporter)  
**Source**: https://4ort.xyz/entity/solute-carrier-family-6-member-3


## References

1. UniProt
2. IUPHAR/BPS Guide to PHARMACOLOGY
3. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL4298139)
4. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL827)
5. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL612)
6. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL405)
7. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL2364614)
8. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1201201)
9. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1194666)
10. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL781)
11. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1722)
12. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL3301595)
13. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1693)
14. [Open Targets Platform](https://platform.opentargets.org/drug/CHEMBL1200483)
15. [InterPro Release 71.0](http://www.ebi.ac.uk/interpro/protein/Q01959)
16. Q20641742
17. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
18. [GOA](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01959&geneProductId=UniProtKB:Q01959)
19. [Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
20. [Effect of torsinA on membrane proteins reveals a loss of function and a dominant-negative phenotype of the dystonia-associated DeltaE-torsinA mutant](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
21. [Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
22. [The Plasma Membrane-Associated GTPase Rin Interacts with the Dopamine Transporter and Is Required for Protein Kinase C-Regulated Dopamine Transporter Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
23. [Redistribution of DAT/α-synuclein complexes visualized by "in situ" proximity ligation assay in transgenic mice modelling early Parkinson's disease](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
24. [GPR37 associates with the dopamine transporter to modulate dopamine uptake and behavioral responses to dopaminergic drugs.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
25. [Identification of a small-molecule inhibitor of the PICK1 PDZ domain that inhibits hippocampal LTP and LTD.](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
26. [Dopamine transporter cell surface localization facilitated by a direct interaction with the dopamine D2 receptor](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
27. [IRIP, a new ischemia/reperfusion-inducible protein that participates in the regulation of transporter activity](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
28. [Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
29. [Amphetamine-induced loss of human dopamine transporter activity: an internalization-dependent and cocaine-sensitive mechanism](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
30. [Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
31. [Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01959&geneProductId=UniProtKB:Q01959)
32. [Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01959&geneProductId=UniProtKB:Q01959)
33. [The Plasma Membrane-Associated GTPase Rin Interacts with the Dopamine Transporter and Is Required for Protein Kinase C-Regulated Dopamine Transporter Trafficking](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01959&geneProductId=UniProtKB:Q01959)
34. [Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT](http://www.ebi.ac.uk/QuickGO/annotations?protein=Q01959&geneProductId=UniProtKB:Q01959)
35. [Flotillin-1 is essential for PKC-triggered endocytosis and membrane microdomain localization of DAT](http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q01959)
36. Ensembl Release 99
37. Identifiers.org
38. Transporter Classification database
39. [OpenAlex](https://docs.openalex.org/download-snapshot/snapshot-data-format)