solute carrier family 4 member 1 (Diego blood group)
type: Thing
alternate name: Diego blood group
alternate name: anion exchanger-1
alternate name: Solute carrier family 4 member 1
alternate name: Swann blood group
alternate name: band 3 anion transport protein
alternate name: Froese blood group
alternate name: solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
alternate name: Wright blood group
alternate name: erythroid anion exchange protein
alternate name: Waldner blood group
description: mammalian protein found in Homo sapiens
additional property: PropertyValue
  property ID: P31
  value: protein
additional property: PropertyValue
  property ID: P352
  value: P02730
additional property: PropertyValue
  property ID: P361
  value: Phosphotransferase/anion transporter
additional property: PropertyValue
  property ID: P361
  value: Anion exchange protein 1
additional property: PropertyValue
  property ID: P361
  value: Bicarbonate transporter, C-terminal domain, protein family
additional property: PropertyValue
  property ID: P373
  value: SLC4A1
additional property: PropertyValue
  property ID: P486
  value: D027963
additional property: PropertyValue
  property ID: P527
  value: Bicarbonate transporter, C-terminal
additional property: PropertyValue
  property ID: P527
  value: Anion exchange, conserved site
additional property: PropertyValue
  property ID: P527
  value: Band 3 cytoplasmic domain
additional property: PropertyValue
  property ID: P637
  value: NP_000333
additional property: PropertyValue
  property ID: P637
  value: XP_005257650
additional property: PropertyValue
  property ID: P637
  value: XP_011523431
additional property: PropertyValue
  property ID: P638
  value: 1BH7
additional property: PropertyValue
  property ID: P638
  value: 1BNX
additional property: PropertyValue
  property ID: P638
  value: 1BTQ
additional property: PropertyValue
  property ID: P646
  value: /m/08q46z
additional property: PropertyValue
  property ID: P672
  value: D12.776.157.530.450.162.193
additional property: PropertyValue
  property ID: P672
  value: D12.776.157.530.450.437.249
additional property: PropertyValue
  property ID: P672
  value: D12.776.157.530.937.656.249
additional property: PropertyValue
  property ID: P680
  value: protein homodimerization activity
additional property: PropertyValue
  property ID: P680
  value: protein-membrane adaptor activity
additional property: PropertyValue
  property ID: P680
  value: chloride transmembrane transporter activity
additional property: PropertyValue
  property ID: P681
  value: integral component of membrane
additional property: PropertyValue
  property ID: P681
  value: blood microparticle
additional property: PropertyValue
  property ID: P681
  value: membrane
additional property: PropertyValue
  property ID: P682
  value: anion transport
additional property: PropertyValue
  property ID: P682
  value: bicarbonate transport
additional property: PropertyValue
  property ID: P682
  value: cellular ion homeostasis
additional property: PropertyValue
  property ID: P692
  value: PBB GE SLC4A1 205592 at fs.png
confidence:
  popularity graph score:
    score: 0.011
    score pct: 1
    tier: established
    components:
      sitelinks: 8
      sitelinks norm: 0.019
      unique citations: 33
      unique citations norm: 0.013
      monthly pageviews: 0
      monthly pageviews norm: 0.0
  sitelinks: 8
  unique citations: 33
  monthly pageviews: 0
  yearly pageviews: 119
  pageview trend:
    m: 2026-06
    v: 76
  pageview trend:
    m: 2026-05
    v: 15
  pageview trend:
    m: 2026-04
    v: 28
  popularity:
    sitelinks: 8
    max: 423
    pct: 1.9
  tier: established
claims:
  P31:
    value: Q8054
    source count: 1
    confidence: 0.2
    value label: protein
  P352:
    value: P02730
    source count: 1
    confidence: 0.2
  P361:
    value: Q24771501
    source count: 1
    confidence: 0.2
    value label: Phosphotransferase/anion transporter
  P361:
    value: Q24783226
    source count: 1
    confidence: 0.2
    value label: Anion exchange protein 1
  P361:
    value: Q83139018
    source count: 1
    confidence: 0.2
    value label: Bicarbonate transporter, C-terminal domain, protein family
  P361:
    value: Q83130489
    source count: 1
    confidence: 0.2
    value label: Band 3 cytoplasmic domain, protein family
  P361:
    value: Q95353422
    source count: 1
    confidence: 0.2
    value label: Anion exchange, conserved site, protein family
  P373:
    value: SLC4A1
    source count: 0
    confidence: 0.0
  P486:
    value: D027963
    source count: 0
    confidence: 0.0
  P527:
    value: Q24767126
    source count: 1
    confidence: 0.2
    value label: Bicarbonate transporter, C-terminal
  P527:
    value: Q24770070
    source count: 1
    confidence: 0.2
    value label: Anion exchange, conserved site
  P527:
    value: Q24719843
    source count: 1
    confidence: 0.2
    value label: Band 3 cytoplasmic domain
  P637:
    value: NP_000333
    source count: 1
    confidence: 0.2
  P637:
    value: XP_005257650
    source count: 1
    confidence: 0.2
  P637:
    value: XP_011523431
    source count: 1
    confidence: 0.2

value: XP_011523432
source count: 1
confidence: 0.2

value: 1BH7
source count: 1
confidence: 0.2

value: 1BNX
source count: 1
confidence: 0.2

value: 1BTQ
source count: 1
confidence: 0.2

value: 1BTR
source count: 1
confidence: 0.2

value: 1BTS
source count: 1
confidence: 0.2

value: /m/08q46z
source count: 1
confidence: 0.2

value: D12.776.157.530.450.162.193
source count: 0
confidence: 0.0

value: D12.776.157.530.450.437.249
source count: 0
confidence: 0.0

value: D12.776.157.530.937.656.249
source count: 0
confidence: 0.0

value: D12.776.543.550.190.276
source count: 0
confidence: 0.0

value: D12.776.543.550.779.249
source count: 0
confidence: 0.0

value: Q14762996
source count: 1
confidence: 0.2
value label: protein homodimerization activity

value: Q14877695
source count: 1
confidence: 0.2
value label: protein-membrane adaptor activity

value: Q14877693
source count: 2
confidence: 0.4
value label: chloride transmembrane transporter activity

value: Q14864384
source count: 1
confidence: 0.2
value label: transporter activity

value: Q14877692
source count: 2
confidence: 0.4
value label: anion transmembrane transporter activity

value: Q14327652
source count: 3
confidence: 0.6
value label: integral component of membrane

value: Q21095089
source count: 1
confidence: 0.2
value label: blood microparticle

value: Q14349455
source count: 3
confidence: 0.6
value label: membrane

value: Q14877690
source count: 2
confidence: 0.4
value label: cortical cytoskeleton

value: Q29548
source count: 3
confidence: 0.6
value label: plasma membrane

value: Q14877696
source count: 3
confidence: 0.6
value label: anion transport

value: Q14864709
source count: 2
confidence: 0.4
value label: bicarbonate transport

value: Q14877697
source count: 1
confidence: 0.2
value label: cellular ion homeostasis

value: Q14864717
source count: 2
confidence: 0.4
value label: chloride transport

value: Q14859673
source count: 1
confidence: 0.2
value label: ion transport

value: PBB GE SLC4A1 205592 at fs.png
source count: 0
confidence: 0.0

value: Q14877701
source count: 1
confidence: 0.2
value label: SLC4A1

value: Q15978631
source count: 1
confidence: 0.2
value label: Homo sapiens

value: ENSP00000262418
source count: 1
confidence: 0.2

value: ENSP00000382190
source count: 1
confidence: 0.2

value: ENSP00000486787
source count: 1
confidence: 0.2

value: science/band-3
source count: 0
confidence: 0.0

value: http://purl.uniprot.org/uniprot/P02730
source count: 1
confidence: 0.2

value: 2776589458
source count: 0
confidence: 0.0

value: 2.A.31.1.1
source count: 2
confidence: 0.4

value: C2776589458
source count: 1
confidence: 0.2

source: The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes
stated in qid: Q24299885
retrieved: 2019-04-08

source: Adducin: structure, function and regulation
stated in qid: Q24290117
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2019-04-08

source: GOA
stated in qid: Q28018111
retrieved: 2017-10-17

source: A new variant of the anion transport protein in human erythrocytes
stated in qid: Q24300339
retrieved: 2019-04-08

source: A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters
stated in qid: Q24338331
retrieved: 2018-01-01

source: Phosphatidylinositol-4,5-biphosphate (PIP2) differentially regulates the interaction of human erythrocyte protein 4.1 (4.1R) with membrane proteins
stated in qid: Q24323334
retrieved: 2019-04-08

source: Transmembrane protein 139 (TMEM139) interacts with human kidney isoform of anion exchanger 1 (kAE1)
stated in qid: Q24338052
retrieved: 2019-04-08

source: Physical and functional links between anion exchanger-1 and sodium pump
stated in qid: Q24300633
retrieved: 2019-04-08

source: Host–parasite interaction: multiple sites in the Plasmodium vivax tryptophan‐rich antigen PvTRAg38 interact with the erythrocyte receptor band 3
stated in qid: Q28115976
retrieved: 2019-04-08

source: Interaction of anion exchanger 1 and glycophorin A in human erythroleukaemic K562 cells
stated in qid: Q38354143
retrieved: 2019-04-08

source: Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains.
stated in qid: Q37216226
retrieved: 2019-04-08

source: Glyceraldehyde 3-phosphate dehydrogenase is required for band 3 (anion exchanger 1) membrane residency in the mammalian kidney
stated in qid: Q28573248
retrieved: 2019-04-08

source: A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters
stated in qid: Q24338331
retrieved: 2018-01-01

source: A structural study of the membrane domain of band 3 by tryptic digestion. Conformational change of band 3 in situ induced by alkali treatment
stated in qid: Q24299904
retrieved: 2019-04-08

source: Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability
stated in qid: Q24315760
retrieved: 2017-10-17

source: A new variant of the anion transport protein in human erythrocytes
stated in qid: Q24300339
retrieved: 2017-10-17

source: The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes
stated in qid: Q24299885
retrieved: 2017-10-17

source: A novel missense mutation in AE1 causing autosomal dominant distal renal tubular acidosis retains normal transport function but is mistargeted in polarized epithelial cells
stated in qid: Q24305531
retrieved: 2019-04-08

source: Non-polarized targeting of AE1 causes autosomal dominant distal renal tubular acidosis
stated in qid: Q24293024
retrieved: 2019-04-08

source: Large-scale proteomics and phosphoproteomics of urinary exosomes
stated in qid: Q24321631
retrieved: 2017-10-17

source: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
stated in qid: Q34211397
retrieved: 2019-04-08

source: Large-scale proteomics and phosphoproteomics of urinary exosomes
stated in qid: Q24321631
retrieved: 2019-04-08

source: Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability
stated in qid: Q24315760
retrieved: 2019-04-08

source: Targeted disruption of the murine erythroid band 3 gene results in spherocytosis and severe haemolytic anaemia despite a normal membrane skeleton
stated in qid: Q24311965
retrieved: 2019-04-08

source: OpenAlex
stated in qid: Q107507571
retrieved: 2022-01-26

source: InterPro Release 71.0
stated in qid: Q58943792

source: Freebase Data Dumps
stated in qid: Q15241312
pub year: 2013

source: UniProt
stated in qid: Q905695
retrieved: 2019-11-13

source: Q20641742
stated in qid: Q20641742
retrieved: 2020-05-30

wikidata id: Q425149
domain: protein
level: standard
html url: https://4ort.xyz/entity/solute-carrier-family-4-member-1-diego-blood-group
markdown url: https://4ort.xyz/entity/solute-carrier-family-4-member-1-diego-blood-group.md
facts url summary: https://4ort.xyz/entity/solute-carrier-family-4-member-1-diego-blood-group/facts.json
facts url standard: https://4ort.xyz/entity/solute-carrier-family-4-member-1-diego-blood-group/facts.json
facts url full: https://4ort.xyz/entity/solute-carrier-family-4-member-1-diego-blood-group/facts.json
data source: Wikidata (CC0 / public domain)
license: https://creativecommons.org/publicdomain/zero/1.0/
api version: v1
served at: 2026-08-06T02:50:37.693742Z
entity updated at: 2026-05-03T18:28:36.114423+00:00Z
entity created at: 2026-04-10T23:14:24.227109+00:00Z